Primary visual area layer 5 spiny 471767045 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Rbp4-Cre_KL100
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001542
Cell_478513443.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001542
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Accommodating Wide AP Multi-Spikers (awMS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -86.30 mV
Rheobase Current Interval (0.18425, 0.18951] nA
Threshold Current Interval (1.28906, 1.34766] nA
Bias Current (to -80.00 mV) 0.0643 nA
Testing Temperature 34.0 °C
Stability Interval [-3.125, 15.0] nA
AP 1-2 Amplitude Drop 12.2820 mV
AP 1 Steady State Amplitude Change 2.4548 mV
AP 1 Amplitude 81.0659 mV
AP 1 Width at Half Height 0.5900 ms
AP 1 Width (Peak To Trough) 4.6100 ms
AP 1 Rate of Change Peak to Trough -18.0388 mV/ms
AP 1 AHP Depth 2.0929 mV
AP2 Amplitude 68.7839 mV
AP2 Width at Half Height 0.6300 ms
AP 2 Width (Peak to Trough) 18.6900 ms
AP 2 Rate of Change Peak to Trough -4.5874 mV/ms
AP 2 AHP Depth 16.9549 mV
AP 1-2 Amplitude Change Percent -15.1506 %
AP 1-2 Half Width Change Percent 6.7797 %
AP 1-2 Rate of Change Peak to Trough Percent Change -74.5691 %
AP 1-2 AHP Depth Percent Change 710.1131 %
Input Resistance 107.9283 MΩ
AP 1 Delay Mean 30.6100 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 37.3000 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 29.8900 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean 14.2857 %
Accommodation Rate to Steady State 0.1580 %/ms
Accommodation at Steady State Mean -88.1047 %
Accommodation Rate Mean at Steady State 20.8962 ms
ISI CV 1.5592
ISI Median 69.4200 ms
ISI Burst Mean Change 693.5725 %
Spike Rate (Strong Stimulation) 71.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 9.2100 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 13.9100 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 9.2400 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2147.9000 ms
Frequency Filter Type High-Pass
Frequency Filter Pass Above 79.3773 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 10370.1 µm2
Number of Stems 14.0
Number of Bifurcations 67.0
Number of Branches 148.0
Overall Width 231.538 µm
Overall Height 656.053 µm
Overall Depth 86.45 µm
Average Diameter 0.410383 µm
Total Length 6735.64 µm
Total Surface 9231.3 µm2
Total Volume 3590.25 µm3
Max Euclidean Distance 580.62 µm
Max Path Distance 719.434 µm
Max Branch Order 19.0
Average Contraction 0.887282
Total Fragmentation 5524.0
Partition Asymmetry 0.5159
Average Rall's Ratio 2.42045
Average Bifurcation Angle Local 74.5074 °
Average Bifurcation Angle Remote 67.3771 °
Fractal Dimension 1.0302
Complexity Summary
State Equations 378
Optimal Time-Step 0.03101 ms
Relative Complexity 15.23 HH
Model Size
Sections 148
Compartments 350
State Equations 378
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.03101 ms
Optimal Time-Step Error 2.79 %
Optimal Time-Step Benchmark Run Time 15.23 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 3.43 %
Max. Stable Time-Step Benchmark Run Time 14.75 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 3692 Hz
CVODE Steps Per AP 1825
CVODE Benchmark Run Time 68.12 HH
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