Primary visual area layer 2/3 spiny 382982932 Cell

Model Type:
Cell
Neurolex IDs: Visual cortex primary layer 2
Visual cortex primary layer 3
Keywords: Mus musculus, Nr5a1-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001541
Cell_473862496.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001541
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Bursters (B)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -83.50 mV
Rheobase Current Interval (0.16869, 0.17120] nA
Threshold Current Interval (0.58594, 0.64453] nA
Bias Current (to -70.00 mV) 0.1481 nA
Testing Temperature 34.0 °C
Stability Interval [-4.0625, 15.0] nA
AP 1-2 Amplitude Drop 4.1569 mV
AP 1 Steady State Amplitude Change N/A mV
AP 1 Amplitude 72.4709 mV
AP 1 Width at Half Height 0.7100 ms
AP 1 Width (Peak To Trough) 5.5900 ms
AP 1 Rate of Change Peak to Trough -15.3230 mV/ms
AP 1 AHP Depth 13.1844 mV
AP2 Amplitude 68.3141 mV
AP2 Width at Half Height 0.7500 ms
AP 2 Width (Peak to Trough) 7.3900 ms
AP 2 Rate of Change Peak to Trough -10.7226 mV/ms
AP 2 AHP Depth 10.9257 mV
AP 1-2 Amplitude Change Percent -5.7359 %
AP 1-2 Half Width Change Percent 5.6338 %
AP 1-2 Rate of Change Peak to Trough Percent Change -30.0229 %
AP 1-2 AHP Depth Percent Change -17.1316 %
Input Resistance 51.3273 MΩ
AP 1 Delay Mean 17.2400 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 35.9200 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 18.4000 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -100.0000 %
Steady State Accommodation Mean -100.0000 %
Accommodation Rate to Steady State N/A %/ms
Accommodation at Steady State Mean -0.0000 %
Accommodation Rate Mean at Steady State 9.3245 ms
ISI CV 26.1591
ISI Median 18.2400 ms
ISI Burst Mean Change -2.9979 %
Spike Rate (Strong Stimulation) 1.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 3.9900 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 13.1000 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 8.1050 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2063.4200 ms
Frequency Filter Type High-Pass
Frequency Filter Pass Above 37.0000 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 9156.89 µm2
Number of Stems 10.0
Number of Bifurcations 26.0
Number of Branches 62.0
Overall Width 177.923 µm
Overall Height 440.426 µm
Overall Depth 76.68 µm
Average Diameter 0.470781 µm
Total Length 3352.64 µm
Total Surface 5461.15 µm2
Total Volume 2922.17 µm3
Max Euclidean Distance 432.913 µm
Max Path Distance 523.915 µm
Max Branch Order 7.0
Average Contraction 0.800412
Total Fragmentation 2552.0
Partition Asymmetry 0.454274
Average Rall's Ratio 2.00222
Average Bifurcation Angle Local 83.3632 °
Average Bifurcation Angle Remote 78.0529 °
Fractal Dimension 1.06387
Complexity Summary
State Equations 195
Optimal Time-Step 0.01042 ms
Relative Complexity 17.84 HH
Model Size
Sections 61
Compartments 179
State Equations 195
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.01042 ms
Optimal Time-Step Error 0.54 %
Optimal Time-Step Benchmark Run Time 17.84 HH
 
Maximum Stable Time-Step 0.125 ms
Maximum Stable Time-Step Error 6.40 %
Max. Stable Time-Step Benchmark Run Time 23.23 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 13080 Hz
CVODE Steps Per AP 843
CVODE Benchmark Run Time 26.30 HH
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