Primary visual area layer 4 aspiny 486783119 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Pvalb-IRES-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001539
Cell_487245869.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001539
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Fast Spikers (FS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -88.55 mV
Rheobase Current Interval (0.13733, 0.14008] nA
Threshold Current Interval (0.64453, 0.70312] nA
Bias Current (to -80.00 mV) 0.0347 nA
Testing Temperature 34.0 °C
Stability Interval [-4.0625, 15.0] nA
AP 1-2 Amplitude Drop -1.1509 mV
AP 1 Steady State Amplitude Change -0.8242 mV
AP 1 Amplitude 60.7563 mV
AP 1 Width at Half Height 0.3500 ms
AP 1 Width (Peak To Trough) 2.5400 ms
AP 1 Rate of Change Peak to Trough -30.8562 mV/ms
AP 1 AHP Depth 17.6185 mV
AP2 Amplitude 61.9072 mV
AP2 Width at Half Height 0.3500 ms
AP 2 Width (Peak to Trough) 2.7000 ms
AP 2 Rate of Change Peak to Trough -29.8608 mV/ms
AP 2 AHP Depth 18.7170 mV
AP 1-2 Amplitude Change Percent 1.8943 %
AP 1-2 Half Width Change Percent 0.0000 %
AP 1-2 Rate of Change Peak to Trough Percent Change -3.2260 %
AP 1-2 AHP Depth Percent Change 6.2346 %
Input Resistance 259.1647 MΩ
AP 1 Delay Mean 25.5900 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 44.3000 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 21.7600 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean 6.6667 %
Accommodation Rate to Steady State 0.0965 %/ms
Accommodation at Steady State Mean -27.1174 %
Accommodation Rate Mean at Steady State 11.2646 ms
ISI CV 31.7089
ISI Median 25.6000 ms
ISI Burst Mean Change 32.6029 %
Spike Rate (Strong Stimulation) 103.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 6.5700 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 13.1400 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 6.8400 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2029.3900 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 9629.15 µm2
Number of Stems 8.0
Number of Bifurcations 17.0
Number of Branches 42.0
Overall Width 309.872 µm
Overall Height 329.745 µm
Overall Depth 38.56 µm
Average Diameter 0.642185 µm
Total Length 2337.18 µm
Total Surface 5234.29 µm2
Total Volume 3228.93 µm3
Max Euclidean Distance 243.918 µm
Max Path Distance 276.149 µm
Max Branch Order 4.0
Average Contraction 0.916029
Total Fragmentation 1931.0
Partition Asymmetry 0.410364
Average Rall's Ratio 3.229
Average Bifurcation Angle Local 72.0512 °
Average Bifurcation Angle Remote 48.064 °
Fractal Dimension 1.02426
Complexity Summary
State Equations 146
Optimal Time-Step 0.02348 ms
Relative Complexity 9.86 HH
Model Size
Sections 42
Compartments 118
State Equations 146
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02348 ms
Optimal Time-Step Error 1.63 %
Optimal Time-Step Benchmark Run Time 9.86 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 3.10 %
Max. Stable Time-Step Benchmark Run Time 7.23 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 4925 Hz
CVODE Steps Per AP 1051
CVODE Benchmark Run Time 23.49 HH
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