Primary visual area layer 5 aspiny 467782778 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Scnn1a-Tg2-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001538
Cell_478513451.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001538
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Non-accommodating Regular Spikers (naRS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -94.76 mV
Rheobase Current Interval (0.42480, 0.43144] nA
Threshold Current Interval (1.64062, 1.69922] nA
Bias Current (to -80.00 mV) 0.1090 nA
Testing Temperature 34.0 °C
Stability Interval [-5.3125, 15.0] nA
AP 1-2 Amplitude Drop -4.8956 mV
AP 1 Steady State Amplitude Change -10.8783 mV
AP 1 Amplitude 33.1864 mV
AP 1 Width at Half Height 0.3500 ms
AP 1 Width (Peak To Trough) 1.2800 ms
AP 1 Rate of Change Peak to Trough -36.6081 mV/ms
AP 1 AHP Depth 13.6720 mV
AP2 Amplitude 38.0820 mV
AP2 Width at Half Height 0.3600 ms
AP 2 Width (Peak to Trough) 1.6700 ms
AP 2 Rate of Change Peak to Trough -31.8922 mV/ms
AP 2 AHP Depth 15.1780 mV
AP 1-2 Amplitude Change Percent 14.7517 %
AP 1-2 Half Width Change Percent 2.8571 %
AP 1-2 Rate of Change Peak to Trough Percent Change -12.8822 %
AP 1-2 AHP Depth Percent Change 11.0153 %
Input Resistance 251.7734 MΩ
AP 1 Delay Mean 35.4200 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 55.2400 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 18.7500 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 22.5806 %
Steady State Accommodation Mean 25.8065 %
Accommodation Rate to Steady State 0.4672 %/ms
Accommodation at Steady State Mean -0.0000 %
Accommodation Rate Mean at Steady State 7.3759 ms
ISI CV 11.5310
ISI Median 10.4900 ms
ISI Burst Mean Change -10.7972 %
Spike Rate (Strong Stimulation) 91.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 7.2600 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 30.6800 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 19.9350 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2060.7300 ms
Frequency Filter Type Low-Pass
Frequency Filter Pass Below 54.9110 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 13717.3 µm2
Number of Stems 8.0
Number of Bifurcations 19.0
Number of Branches 46.0
Overall Width 308.296 µm
Overall Height 312.313 µm
Overall Depth 51.37 µm
Average Diameter 0.353912 µm
Total Length 3780.71 µm
Total Surface 5005.11 µm2
Total Volume 3870.52 µm3
Max Euclidean Distance 331.671 µm
Max Path Distance 376.811 µm
Max Branch Order 4.0
Average Contraction 0.923624
Total Fragmentation 3182.0
Partition Asymmetry 0.412281
Average Rall's Ratio 2.2
Average Bifurcation Angle Local 66.1208 °
Average Bifurcation Angle Remote 53.5593 °
Fractal Dimension 1.01629
Complexity Summary
State Equations 216
Optimal Time-Step 0.02365 ms
Relative Complexity 12.04 HH
Model Size
Sections 46
Compartments 188
State Equations 216
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02365 ms
Optimal Time-Step Error 1.59 %
Optimal Time-Step Benchmark Run Time 12.04 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 4.36 %
Max. Stable Time-Step Benchmark Run Time 8.90 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 7954 Hz
CVODE Steps Per AP 921
CVODE Benchmark Run Time 32.14 HH
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