Primary visual area layer 2/3 aspiny 473540161 Cell

Model Type:
Cell
Neurolex IDs: Visual cortex primary layer 2
Visual cortex primary layer 3
Keywords: Mus musculus, Sst-IRES-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001537
Cell_476637699.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001537
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Regular Spikers (RS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -80.31 mV
Rheobase Current Interval (0.05905, 0.06042] nA
Threshold Current Interval (0.29297, 0.35156] nA
Bias Current (to -70.00 mV) 0.0523 nA
Testing Temperature 34.0 °C
Stability Interval [-4.0625, 15.0] nA
AP 1-2 Amplitude Drop -0.6841 mV
AP 1 Steady State Amplitude Change -1.1788 mV
AP 1 Amplitude 71.7044 mV
AP 1 Width at Half Height 0.3600 ms
AP 1 Width (Peak To Trough) 2.3700 ms
AP 1 Rate of Change Peak to Trough -35.7013 mV/ms
AP 1 AHP Depth 12.9076 mV
AP2 Amplitude 72.3885 mV
AP2 Width at Half Height 0.3700 ms
AP 2 Width (Peak to Trough) 2.6200 ms
AP 2 Rate of Change Peak to Trough -33.0375 mV/ms
AP 2 AHP Depth 14.1697 mV
AP 1-2 Amplitude Change Percent 0.9540 %
AP 1-2 Half Width Change Percent 2.7778 %
AP 1-2 Rate of Change Peak to Trough Percent Change -7.4614 %
AP 1-2 AHP Depth Percent Change 9.7778 %
Input Resistance 160.7811 MΩ
AP 1 Delay Mean 26.2500 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 43.1100 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 21.9450 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -46.1538 %
Steady State Accommodation Mean -46.1538 %
Accommodation Rate to Steady State -0.0414 %/ms
Accommodation at Steady State Mean -64.5140 %
Accommodation Rate Mean at Steady State 571.4573 ms
ISI CV 4.0214
ISI Median 51.0000 ms
ISI Burst Mean Change 60.3203 %
Spike Rate (Strong Stimulation) 80.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 7.9700 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 13.7100 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 5.7800 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2068.2600 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 6551.82 µm2
Number of Stems 5.0
Number of Bifurcations 24.0
Number of Branches 53.0
Overall Width 264.787 µm
Overall Height 226.735 µm
Overall Depth 51.63 µm
Average Diameter 0.385973 µm
Total Length 2486.34 µm
Total Surface 3537.4 µm2
Total Volume 1982.79 µm3
Max Euclidean Distance 211.777 µm
Max Path Distance 240.878 µm
Max Branch Order 5.0
Average Contraction 0.894228
Total Fragmentation 2314.0
Partition Asymmetry 0.485119
Average Rall's Ratio 2.58682
Average Bifurcation Angle Local 74.1883 °
Average Bifurcation Angle Remote 57.5816 °
Fractal Dimension 1.03044
Complexity Summary
State Equations 153
Optimal Time-Step 0.02316 ms
Relative Complexity 10.57 HH
Model Size
Sections 53
Compartments 125
State Equations 153
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02316 ms
Optimal Time-Step Error 1.15 %
Optimal Time-Step Benchmark Run Time 10.57 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 2.59 %
Max. Stable Time-Step Benchmark Run Time 7.65 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 4284 Hz
CVODE Steps Per AP 1149
CVODE Benchmark Run Time 25.38 HH
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