Primary visual area layer 2/3 spiny 318808427 Cell

Model Type:
Cell
Neurolex IDs: Visual cortex primary layer 2
Visual cortex primary layer 3
Keywords: Mus musculus, Nr5a1-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001535
Cell_473863035.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001535
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Accommodating Wide AP Multi-Spikers (awMS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -89.26 mV
Rheobase Current Interval (0.10323, 0.10574] nA
Threshold Current Interval (0.58594, 0.64453] nA
Bias Current (to -80.00 mV) 0.0332 nA
Testing Temperature 34.0 °C
Stability Interval [-2.1875, 15.0] nA
AP 1-2 Amplitude Drop 8.3337 mV
AP 1 Steady State Amplitude Change 8.3337 mV
AP 1 Amplitude 74.0741 mV
AP 1 Width at Half Height 0.6400 ms
AP 1 Width (Peak To Trough) 10.3300 ms
AP 1 Rate of Change Peak to Trough -9.1305 mV/ms
AP 1 AHP Depth 20.2444 mV
AP2 Amplitude 65.7404 mV
AP2 Width at Half Height 0.6600 ms
AP 2 Width (Peak to Trough) 11.7100 ms
AP 2 Rate of Change Peak to Trough -7.4598 mV/ms
AP 2 AHP Depth 21.6141 mV
AP 1-2 Amplitude Change Percent -11.2505 %
AP 1-2 Half Width Change Percent 3.1250 %
AP 1-2 Rate of Change Peak to Trough Percent Change -18.2982 %
AP 1-2 AHP Depth Percent Change 6.7656 %
Input Resistance 271.5261 MΩ
AP 1 Delay Mean 28.5400 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 1966.6600 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean N/A ms
Burst 1 ISI SD N/A ms
Initial Accommodation Mean -100.0000 %
Steady State Accommodation Mean 0.0000 %
Accommodation Rate to Steady State N/A %/ms
Accommodation at Steady State Mean N/A %
Accommodation Rate Mean at Steady State N/A ms
ISI CV N/A
ISI Median 1938.1200 ms
ISI Burst Mean Change N/A %
Spike Rate (Strong Stimulation) 54.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 8.4900 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 28.3100 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 19.7850 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2054.3300 ms
Frequency Filter Type High-Pass
Frequency Filter Pass Above 52.5864 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 6714.48 µm2
Number of Stems 5.0
Number of Bifurcations 17.0
Number of Branches 39.0
Overall Width 345.751 µm
Overall Height 190.768 µm
Overall Depth 34.53 µm
Average Diameter 0.563676 µm
Total Length 1961.48 µm
Total Surface 3904.27 µm2
Total Volume 2200.24 µm3
Max Euclidean Distance 340.946 µm
Max Path Distance 370.397 µm
Max Branch Order 4.0
Average Contraction 0.852372
Total Fragmentation 1517.0
Partition Asymmetry 0.263305
Average Rall's Ratio 2.14187
Average Bifurcation Angle Local 72.6774 °
Average Bifurcation Angle Remote 56.2593 °
Fractal Dimension 1.04977
Complexity Summary
State Equations 117
Optimal Time-Step 0.00752 ms
Relative Complexity 16.81 HH
Model Size
Sections 39
Compartments 101
State Equations 117
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00752 ms
Optimal Time-Step Error 0.01 %
Optimal Time-Step Benchmark Run Time 16.81 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 0.06 %
Max. Stable Time-Step Benchmark Run Time 31.60 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 12154 Hz
CVODE Steps Per AP 3246
CVODE Benchmark Run Time 37.08 HH
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