Primary visual area layer 4 spiny 320668879 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Scnn1a-Tg2-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001533
Cell_472300877.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001533
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Accommodating Wide AP Multi-Spikers (awMS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -88.66 mV
Rheobase Current Interval (0.09270, 0.09613] nA
Threshold Current Interval (0.82031, 0.87891] nA
Bias Current (to -80.00 mV) 0.0500 nA
Testing Temperature 34.0 °C
Stability Interval [-3.125, 15.0] nA
AP 1-2 Amplitude Drop 3.6141 mV
AP 1 Steady State Amplitude Change N/A mV
AP 1 Amplitude 53.7192 mV
AP 1 Width at Half Height 0.8500 ms
AP 1 Width (Peak To Trough) 13.7400 ms
AP 1 Rate of Change Peak to Trough -5.1194 mV/ms
AP 1 AHP Depth 16.6220 mV
AP2 Amplitude 50.1051 mV
AP2 Width at Half Height 0.9100 ms
AP 2 Width (Peak to Trough) 18.2700 ms
AP 2 Rate of Change Peak to Trough -3.5988 mV/ms
AP 2 AHP Depth 15.6459 mV
AP 1-2 Amplitude Change Percent -6.7277 %
AP 1-2 Half Width Change Percent 7.0588 %
AP 1-2 Rate of Change Peak to Trough Percent Change -29.7024 %
AP 1-2 AHP Depth Percent Change -5.8727 %
Input Resistance 159.7316 MΩ
AP 1 Delay Mean 40.8300 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 89.0600 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 46.6800 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -62.5000 %
Steady State Accommodation Mean -100.0000 %
Accommodation Rate to Steady State N/A %/ms
Accommodation at Steady State Mean -0.0000 %
Accommodation Rate Mean at Steady State 35.6617 ms
ISI CV 22.7163
ISI Median 46.0300 ms
ISI Burst Mean Change -6.4275 %
Spike Rate (Strong Stimulation) 1.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 13.0800 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 27.1000 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) N/A ms
Burst 1 ISI SD (Strong Stimulation) N/A ms
Ramp First Spike Time 2068.5900 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 12394.4 µm2
Number of Stems 13.0
Number of Bifurcations 80.0
Number of Branches 173.0
Overall Width 237.56 µm
Overall Height 523.282 µm
Overall Depth 79.76 µm
Average Diameter 0.47996 µm
Total Length 5331.18 µm
Total Surface 8650.89 µm2
Total Volume 4132.8 µm3
Max Euclidean Distance 447.056 µm
Max Path Distance 737.594 µm
Max Branch Order 15.0
Average Contraction 0.797471
Total Fragmentation 4190.0
Partition Asymmetry 0.647377
Average Rall's Ratio 2.5713
Average Bifurcation Angle Local 86.4528 °
Average Bifurcation Angle Remote 85.0387 °
Fractal Dimension 1.11275
Complexity Summary
State Equations 336
Optimal Time-Step 0.01235 ms
Relative Complexity 29.37 HH
Model Size
Sections 170
Compartments 320
State Equations 336
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.01235 ms
Optimal Time-Step Error 0.23 %
Optimal Time-Step Benchmark Run Time 29.37 HH
 
Maximum Stable Time-Step 0.125 ms
Maximum Stable Time-Step Error 2.38 %
Max. Stable Time-Step Benchmark Run Time 45.33 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 14672 Hz
CVODE Steps Per AP 624
CVODE Benchmark Run Time 49.87 HH
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