Primary visual area layer 4 aspiny 474626527 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Htr3a-Cre_NO152, pyramidal
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001532
Cell_477494382.cell.nml
( view NeuroML )
NMLCH000104
Ih.channel.nml
( view NeuroML )
NMLCH000114
pas.channel.nml
( view NeuroML )
NMLCH000129
Kd.channel.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001532
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Regular Spikers (RS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -77.42 mV
Rheobase Current Interval (0.04807, 0.04921] nA
Threshold Current Interval (0.23438, 0.29297] nA
Bias Current (to -70.00 mV) 0.0347 nA
Testing Temperature 34.0 °C
Stability Interval [-0.9375, 15.0] nA
AP 1-2 Amplitude Drop 1.7218 mV
AP 1 Steady State Amplitude Change 1.3104 mV
AP 1 Amplitude 60.2612 mV
AP 1 Width at Half Height 0.7300 ms
AP 1 Width (Peak To Trough) 5.1800 ms
AP 1 Rate of Change Peak to Trough -13.5555 mV/ms
AP 1 AHP Depth 9.9561 mV
AP2 Amplitude 58.5394 mV
AP2 Width at Half Height 0.7300 ms
AP 2 Width (Peak to Trough) 16.0900 ms
AP 2 Rate of Change Peak to Trough -4.4246 mV/ms
AP 2 AHP Depth 12.6518 mV
AP 1-2 Amplitude Change Percent -2.8572 %
AP 1-2 Half Width Change Percent 0.0000 %
AP 1-2 Rate of Change Peak to Trough Percent Change -67.3595 %
AP 1-2 AHP Depth Percent Change 27.0765 %
Input Resistance 178.7117 MΩ
AP 1 Delay Mean 20.8100 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 35.8300 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 27.2700 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -18.1818 %
Steady State Accommodation Mean -27.2727 %
Accommodation Rate to Steady State -0.0354 %/ms
Accommodation at Steady State Mean -44.9555 %
Accommodation Rate Mean at Steady State 287.2300 ms
ISI CV 7.2509
ISI Median 47.0550 ms
ISI Burst Mean Change 163.1158 %
Spike Rate (Strong Stimulation) 59.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 6.5500 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 13.3100 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 25.3950 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2090.0400 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 5469.31 µm2
Number of Stems 5.0
Number of Bifurcations 13.0
Number of Branches 31.0
Overall Width 166.86 µm
Overall Height 353.082 µm
Overall Depth 54.83 µm
Average Diameter 0.380223 µm
Total Length 1424.61 µm
Total Surface 2121.76 µm2
Total Volume 1558.07 µm3
Max Euclidean Distance 321.64 µm
Max Path Distance 373.432 µm
Max Branch Order 5.0
Average Contraction 0.914542
Total Fragmentation 1146.0
Partition Asymmetry 0.564103
Average Rall's Ratio 2.25375
Average Bifurcation Angle Local 72.2397 °
Average Bifurcation Angle Remote 55.8298 °
Fractal Dimension 1.02413
Complexity Summary
Relative Complexity 19.74 HH
State Equations 102
Optimal Time-Step 0.02445 ms
Model Size
Sections 32
Compartments 74
State Equations 102
Variable Time-Step Complexity
CVODE Steady State Step Frequency 4410 Hz
CVODE Steps Per AP 970
CVODE Benchmark Run Time 19.74 HH
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