Primary visual area layer 6a aspiny 466245544 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 6a
Keywords: Mus musculus, Pvalb-IRES-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001531
Cell_471081668.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001531
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Non-accommodating Regular Spikers (naRS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -84.18 mV
Rheobase Current Interval (0.01945, 0.02335] nA
Threshold Current Interval (0.93750, 0.99609] nA
Bias Current (to -70.00 mV) 0.0194 nA
Testing Temperature 34.0 °C
Stability Interval [-8.4375, 15.0] nA
AP 1-2 Amplitude Drop -0.8089 mV
AP 1 Steady State Amplitude Change -0.8815 mV
AP 1 Amplitude 60.1200 mV
AP 1 Width at Half Height 0.4500 ms
AP 1 Width (Peak To Trough) 3.5100 ms
AP 1 Rate of Change Peak to Trough -22.3240 mV/ms
AP 1 AHP Depth 18.2371 mV
AP2 Amplitude 60.9289 mV
AP2 Width at Half Height 0.4600 ms
AP 2 Width (Peak to Trough) 3.3900 ms
AP 2 Rate of Change Peak to Trough -23.1851 mV/ms
AP 2 AHP Depth 17.6687 mV
AP 1-2 Amplitude Change Percent 1.3455 %
AP 1-2 Half Width Change Percent 2.2222 %
AP 1-2 Rate of Change Peak to Trough Percent Change 3.8576 %
AP 1-2 AHP Depth Percent Change -3.1167 %
Input Resistance 528.6768 MΩ
AP 1 Delay Mean 163.1300 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 203.0900 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 40.3350 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 66.6667 %
Steady State Accommodation Mean 66.6667 %
Accommodation Rate to Steady State 0.3283 %/ms
Accommodation at Steady State Mean -3.3045 %
Accommodation Rate Mean at Steady State 108.6762 ms
ISI CV 151.1844
ISI Median 41.4900 ms
ISI Burst Mean Change 1.8769 %
Spike Rate (Strong Stimulation) 45.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 63.0300 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 83.5800 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 20.7350 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2174.3900 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 6260.46 µm2
Number of Stems 9.0
Number of Bifurcations 19.0
Number of Branches 47.0
Overall Width 300.213 µm
Overall Height 411.367 µm
Overall Depth 101.55 µm
Average Diameter 0.392337 µm
Total Length 3114.34 µm
Total Surface 4302.47 µm2
Total Volume 2001.6 µm3
Max Euclidean Distance 375.06 µm
Max Path Distance 500.79 µm
Max Branch Order 5.0
Average Contraction 0.887395
Total Fragmentation 2522.0
Partition Asymmetry 0.5
Average Rall's Ratio 2.58636
Average Bifurcation Angle Local 70.7774 °
Average Bifurcation Angle Remote 50.2103 °
Fractal Dimension 1.02978
Complexity Summary
State Equations 185
Optimal Time-Step 0.02304 ms
Relative Complexity 12.14 HH
Model Size
Sections 47
Compartments 157
State Equations 185
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02304 ms
Optimal Time-Step Error 1.13 %
Optimal Time-Step Benchmark Run Time 12.14 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 2.50 %
Max. Stable Time-Step Benchmark Run Time 8.74 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 4044 Hz
CVODE Steps Per AP 397
CVODE Benchmark Run Time 14.73 HH
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