Primary visual area layer 5 spiny 468120757 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Scnn1a-Tg3-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001530
Cell_473871773.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001530
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Non-accommodating Regular Spikers (naRS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -83.61 mV
Rheobase Current Interval (0.23918, 0.24353] nA
Threshold Current Interval (1.05469, 1.11328] nA
Bias Current (to -70.00 mV) 0.1364 nA
Testing Temperature 34.0 °C
Stability Interval [-4.0625, 15.0] nA
AP 1-2 Amplitude Drop 2.5989 mV
AP 1 Steady State Amplitude Change 2.3610 mV
AP 1 Amplitude 69.6300 mV
AP 1 Width at Half Height 0.6600 ms
AP 1 Width (Peak To Trough) 40.4600 ms
AP 1 Rate of Change Peak to Trough -2.7356 mV/ms
AP 1 AHP Depth 41.0510 mV
AP2 Amplitude 67.0310 mV
AP2 Width at Half Height 0.6700 ms
AP 2 Width (Peak to Trough) 25.7400 ms
AP 2 Rate of Change Peak to Trough -3.2859 mV/ms
AP 2 AHP Depth 17.5472 mV
AP 1-2 Amplitude Change Percent -3.7325 %
AP 1-2 Half Width Change Percent 1.5152 %
AP 1-2 Rate of Change Peak to Trough Percent Change 20.1166 %
AP 1-2 AHP Depth Percent Change -57.2551 %
Input Resistance 100.3418 MΩ
AP 1 Delay Mean 26.3500 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 1081.9500 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 662.4900 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean 100.0000 %
Accommodation Rate to Steady State 0.0924 %/ms
Accommodation at Steady State Mean -0.0000 %
Accommodation Rate Mean at Steady State 10.0000 ms
ISI CV 1.3648
ISI Median 268.8200 ms
ISI Burst Mean Change -74.4809 %
Spike Rate (Strong Stimulation) 3.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 5.8400 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 1136.5300 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 641.8450 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2060.7700 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 17787.0 µm2
Number of Stems 13.0
Number of Bifurcations 39.0
Number of Branches 91.0
Overall Width 222.517 µm
Overall Height 619.466 µm
Overall Depth 105.9 µm
Average Diameter 0.44757 µm
Total Length 4834.67 µm
Total Surface 7555.33 µm2
Total Volume 5272.38 µm3
Max Euclidean Distance 558.72 µm
Max Path Distance 662.346 µm
Max Branch Order 9.0
Average Contraction 0.842881
Total Fragmentation 3669.0
Partition Asymmetry 0.460633
Average Rall's Ratio 1.88667
Average Bifurcation Angle Local 73.4427 °
Average Bifurcation Angle Remote 60.6496 °
Fractal Dimension 1.05119
Complexity Summary
State Equations 271
Optimal Time-Step 0.00758 ms
Relative Complexity 36.70 HH
Model Size
Sections 91
Compartments 255
State Equations 271
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00758 ms
Optimal Time-Step Error 0.29 %
Optimal Time-Step Benchmark Run Time 36.70 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 1.85 %
Max. Stable Time-Step Benchmark Run Time 69.57 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 15011 Hz
CVODE Steps Per AP -447
CVODE Benchmark Run Time 19.27 HH
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