Primary visual area layer 4 spiny 476616076 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Rorb-IRES2-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001527
Cell_478810017.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001527
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Regular Spikers (RS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -82.84 mV
Rheobase Current Interval (0.07004, 0.07210] nA
Threshold Current Interval (0.46875, 0.52734] nA
Bias Current (to -70.00 mV) 0.0674 nA
Testing Temperature 34.0 °C
Stability Interval [-6.25, 15.0] nA
AP 1-2 Amplitude Drop 0.1489 mV
AP 1 Steady State Amplitude Change 0.1613 mV
AP 1 Amplitude 88.7651 mV
AP 1 Width at Half Height 0.7600 ms
AP 1 Width (Peak To Trough) 6.5100 ms
AP 1 Rate of Change Peak to Trough -15.2280 mV/ms
AP 1 AHP Depth 10.3690 mV
AP2 Amplitude 88.6162 mV
AP2 Width at Half Height 0.7700 ms
AP 2 Width (Peak to Trough) 7.7900 ms
AP 2 Rate of Change Peak to Trough -13.1756 mV/ms
AP 2 AHP Depth 14.0219 mV
AP 1-2 Amplitude Change Percent -0.1678 %
AP 1-2 Half Width Change Percent 1.3158 %
AP 1-2 Rate of Change Peak to Trough Percent Change -13.4775 %
AP 1-2 AHP Depth Percent Change 35.2295 %
Input Resistance 102.8114 MΩ
AP 1 Delay Mean 24.7700 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 42.5300 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 26.5300 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -16.6667 %
Steady State Accommodation Mean -16.6667 %
Accommodation Rate to Steady State -0.0233 %/ms
Accommodation at Steady State Mean -31.2017 %
Accommodation Rate Mean at Steady State 230.3856 ms
ISI CV 11.0894
ISI Median 38.5100 ms
ISI Burst Mean Change 98.7613 %
Spike Rate (Strong Stimulation) 1.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 8.8800 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 15.0000 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 5.6550 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2078.7100 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 5099.96 µm2
Number of Stems 7.0
Number of Bifurcations 28.0
Number of Branches 63.0
Overall Width 170.503 µm
Overall Height 439.37 µm
Overall Depth 55.79 µm
Average Diameter 0.580311 µm
Total Length 2602.29 µm
Total Surface 5146.25 µm2
Total Volume 2088.1 µm3
Max Euclidean Distance 438.843 µm
Max Path Distance 472.019 µm
Max Branch Order 9.0
Average Contraction 0.927584
Total Fragmentation 2046.0
Partition Asymmetry 0.5
Average Rall's Ratio 2.76
Average Bifurcation Angle Local 77.5052 °
Average Bifurcation Angle Remote 64.9133 °
Fractal Dimension 1.01961
Complexity Summary
State Equations 169
Optimal Time-Step 0.02717 ms
Relative Complexity 11.00 HH
Model Size
Sections 63
Compartments 141
State Equations 169
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02717 ms
Optimal Time-Step Error 2.91 %
Optimal Time-Step Benchmark Run Time 11.00 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 3.74 %
Max. Stable Time-Step Benchmark Run Time 9.34 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 4768 Hz
CVODE Steps Per AP 608
CVODE Benchmark Run Time 21.32 HH
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