Primary visual area layer 4 spiny 397351623 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Nr5a1-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001526
Cell_472306544.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001526
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Regular Spikers (RS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -92.32 mV
Rheobase Current Interval (0.05974, 0.06223] nA
Threshold Current Interval (0.58411, 0.63721] nA
Bias Current (to -80.00 mV) 0.0220 nA
Testing Temperature 34.0 °C
Stability Interval [-1.5625, 13.59375] nA
AP 1-2 Amplitude Drop 1.2149 mV
AP 1 Steady State Amplitude Change 4.1746 mV
AP 1 Amplitude 63.0589 mV
AP 1 Width at Half Height 0.8900 ms
AP 1 Width (Peak To Trough) 9.9000 ms
AP 1 Rate of Change Peak to Trough -7.8883 mV/ms
AP 1 AHP Depth 15.0351 mV
AP2 Amplitude 61.8439 mV
AP2 Width at Half Height 0.8800 ms
AP 2 Width (Peak to Trough) 10.2700 ms
AP 2 Rate of Change Peak to Trough -7.5934 mV/ms
AP 2 AHP Depth 16.1404 mV
AP 1-2 Amplitude Change Percent -1.9267 %
AP 1-2 Half Width Change Percent -1.1236 %
AP 1-2 Rate of Change Peak to Trough Percent Change -3.7380 %
AP 1-2 AHP Depth Percent Change 7.3516 %
Input Resistance 562.4056 MΩ
AP 1 Delay Mean 99.7400 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 147.5500 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 85.9750 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean 0.0000 %
Accommodation Rate to Steady State 0.0000 %/ms
Accommodation at Steady State Mean -73.2092 %
Accommodation Rate Mean at Steady State 94.4772 ms
ISI CV 4.1778
ISI Median 162.7850 ms
ISI Burst Mean Change 159.6528 %
Spike Rate (Strong Stimulation) 36.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 27.8200 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 55.9200 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 28.3900 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2086.7000 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 6106.32 µm2
Number of Stems 6.0
Number of Bifurcations 20.0
Number of Branches 46.0
Overall Width 180.621 µm
Overall Height 381.871 µm
Overall Depth 58.56 µm
Average Diameter 0.495453 µm
Total Length 2251.98 µm
Total Surface 3926.2 µm2
Total Volume 2032.76 µm3
Max Euclidean Distance 436.431 µm
Max Path Distance 461.493 µm
Max Branch Order 6.0
Average Contraction 0.891507
Total Fragmentation 2156.0
Partition Asymmetry 0.453485
Average Rall's Ratio 1.93
Average Bifurcation Angle Local 55.4744 °
Average Bifurcation Angle Remote 62.3924 °
Fractal Dimension 1.02863
Complexity Summary
State Equations 130
Optimal Time-Step 0.01074 ms
Relative Complexity 13.85 HH
Model Size
Sections 46
Compartments 114
State Equations 130
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.01074 ms
Optimal Time-Step Error 0.05 %
Optimal Time-Step Benchmark Run Time 13.85 HH
 
Maximum Stable Time-Step 0.125 ms
Maximum Stable Time-Step Error 0.62 %
Max. Stable Time-Step Benchmark Run Time 18.59 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 11759 Hz
CVODE Steps Per AP 491
CVODE Benchmark Run Time 16.30 HH
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