Primary visual area layer 5 spiny 314804042 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Rorb-IRES2-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001525
Cell_473863510.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001525
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Regular Spikers (RS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -85.71 mV
Rheobase Current Interval (0.09888, 0.10162] nA
Threshold Current Interval (0.64453, 0.70312] nA
Bias Current (to -80.00 mV) 0.0223 nA
Testing Temperature 34.0 °C
Stability Interval [-2.8125, 15.0] nA
AP 1-2 Amplitude Drop 1.0483 mV
AP 1 Steady State Amplitude Change 5.9192 mV
AP 1 Amplitude 70.1514 mV
AP 1 Width at Half Height 0.6300 ms
AP 1 Width (Peak To Trough) 5.7000 ms
AP 1 Rate of Change Peak to Trough -15.2715 mV/ms
AP 1 AHP Depth 16.8959 mV
AP2 Amplitude 69.1031 mV
AP2 Width at Half Height 0.6400 ms
AP 2 Width (Peak to Trough) 5.8800 ms
AP 2 Rate of Change Peak to Trough -14.7183 mV/ms
AP 2 AHP Depth 17.4405 mV
AP 1-2 Amplitude Change Percent -1.4944 %
AP 1-2 Half Width Change Percent 1.5873 %
AP 1-2 Rate of Change Peak to Trough Percent Change -3.6222 %
AP 1-2 AHP Depth Percent Change 3.2229 %
Input Resistance 259.7540 MΩ
AP 1 Delay Mean 34.6600 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 66.0100 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 32.6200 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -42.8571 %
Steady State Accommodation Mean -42.8571 %
Accommodation Rate to Steady State -0.0920 %/ms
Accommodation at Steady State Mean -81.5001 %
Accommodation Rate Mean at Steady State 190.8437 ms
ISI CV 3.3383
ISI Median 104.8000 ms
ISI Burst Mean Change 8.1021 %
Spike Rate (Strong Stimulation) 54.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 10.4800 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 24.8800 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 14.8800 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2063.5300 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 6096.44 µm2
Number of Stems 5.0
Number of Bifurcations 29.0
Number of Branches 63.0
Overall Width 192.143 µm
Overall Height 429.939 µm
Overall Depth 52.0 µm
Average Diameter 0.527983 µm
Total Length 2544.06 µm
Total Surface 4689.78 µm2
Total Volume 2197.29 µm3
Max Euclidean Distance 417.285 µm
Max Path Distance 447.508 µm
Max Branch Order 8.0
Average Contraction 0.89681
Total Fragmentation 2149.0
Partition Asymmetry 0.413465
Average Rall's Ratio 2.01267
Average Bifurcation Angle Local 69.6836 °
Average Bifurcation Angle Remote 65.4603 °
Fractal Dimension 1.03471
Complexity Summary
State Equations 149
Optimal Time-Step 0.01099 ms
Relative Complexity 15.43 HH
Model Size
Sections 63
Compartments 133
State Equations 149
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.01099 ms
Optimal Time-Step Error 0.44 %
Optimal Time-Step Benchmark Run Time 15.43 HH
 
Maximum Stable Time-Step 0.125 ms
Maximum Stable Time-Step Error 1.62 %
Max. Stable Time-Step Benchmark Run Time 21.18 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 11274 Hz
CVODE Steps Per AP 871
CVODE Benchmark Run Time 22.27 HH
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