Primary visual area layer 5 sparsely spiny 324466858 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Sst-IRES-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001524
Cell_473835796.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001524
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Regular Spikers (RS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -91.45 mV
Rheobase Current Interval (0.08949, 0.09338] nA
Threshold Current Interval (0.93750, 0.99609] nA
Bias Current (to -80.00 mV) 0.0472 nA
Testing Temperature 34.0 °C
Stability Interval [-1.5625, 15.0] nA
AP 1-2 Amplitude Drop 2.1935 mV
AP 1 Steady State Amplitude Change 6.2927 mV
AP 1 Amplitude 59.4824 mV
AP 1 Width at Half Height 0.7100 ms
AP 1 Width (Peak To Trough) 4.0400 ms
AP 1 Rate of Change Peak to Trough -19.1625 mV/ms
AP 1 AHP Depth 17.9340 mV
AP2 Amplitude 57.2889 mV
AP2 Width at Half Height 0.7100 ms
AP 2 Width (Peak to Trough) 4.3200 ms
AP 2 Rate of Change Peak to Trough -17.7717 mV/ms
AP 2 AHP Depth 19.4848 mV
AP 1-2 Amplitude Change Percent -3.6877 %
AP 1-2 Half Width Change Percent -0.0000 %
AP 1-2 Rate of Change Peak to Trough Percent Change -7.2579 %
AP 1-2 AHP Depth Percent Change 8.6471 %
Input Resistance 204.7134 MΩ
AP 1 Delay Mean 53.0600 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 78.6400 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 26.8000 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -60.0000 %
Steady State Accommodation Mean -60.0000 %
Accommodation Rate to Steady State -0.0746 %/ms
Accommodation at Steady State Mean -88.8133 %
Accommodation Rate Mean at Steady State 493.2114 ms
ISI CV 2.1539
ISI Median 96.2650 ms
ISI Burst Mean Change 9.5387 %
Spike Rate (Strong Stimulation) 26.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 17.4300 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 29.3800 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 12.4900 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2159.8600 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 12276.8 µm2
Number of Stems 8.0
Number of Bifurcations 19.0
Number of Branches 46.0
Overall Width 353.503 µm
Overall Height 481.034 µm
Overall Depth 86.34 µm
Average Diameter 0.522563 µm
Total Length 4189.14 µm
Total Surface 7633.2 µm2
Total Volume 4098.85 µm3
Max Euclidean Distance 382.815 µm
Max Path Distance 442.802 µm
Max Branch Order 5.0
Average Contraction 0.912863
Total Fragmentation 3479.0
Partition Asymmetry 0.47619
Average Rall's Ratio 3.471
Average Bifurcation Angle Local 60.4287 °
Average Bifurcation Angle Remote 60.2403 °
Fractal Dimension 1.02613
Complexity Summary
State Equations 224
Optimal Time-Step 0.00762 ms
Relative Complexity 30.13 HH
Model Size
Sections 46
Compartments 208
State Equations 224
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00762 ms
Optimal Time-Step Error 0.24 %
Optimal Time-Step Benchmark Run Time 30.13 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 1.82 %
Max. Stable Time-Step Benchmark Run Time 57.40 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 14093 Hz
CVODE Steps Per AP 858
CVODE Benchmark Run Time 34.23 HH
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