Primary visual area layer 2/3 spiny 480124551 Cell

Model Type:
Cell
Neurolex IDs: Visual cortex primary layer 2
Visual cortex primary layer 3
Keywords: Mus musculus, Rorb-IRES2-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001522
Cell_482657381.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001522
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Regular Spikers (RS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -86.71 mV
Rheobase Current Interval (0.07324, 0.07507] nA
Threshold Current Interval (0.41016, 0.46875] nA
Bias Current (to -80.00 mV) 0.0220 nA
Testing Temperature 34.0 °C
Stability Interval [-0.625, 15.0] nA
AP 1-2 Amplitude Drop -2.3660 mV
AP 1 Steady State Amplitude Change 8.5375 mV
AP 1 Amplitude 62.3075 mV
AP 1 Width at Half Height 0.5800 ms
AP 1 Width (Peak To Trough) 2.6200 ms
AP 1 Rate of Change Peak to Trough -30.5664 mV/ms
AP 1 AHP Depth 17.7765 mV
AP2 Amplitude 64.6735 mV
AP2 Width at Half Height 0.5700 ms
AP 2 Width (Peak to Trough) 2.5800 ms
AP 2 Rate of Change Peak to Trough -31.8122 mV/ms
AP 2 AHP Depth 17.4021 mV
AP 1-2 Amplitude Change Percent 3.7973 %
AP 1-2 Half Width Change Percent -1.7241 %
AP 1-2 Rate of Change Peak to Trough Percent Change 4.0758 %
AP 1-2 AHP Depth Percent Change -2.1064 %
Input Resistance 218.8739 MΩ
AP 1 Delay Mean 33.9300 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 46.4300 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 13.3150 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -80.0000 %
Steady State Accommodation Mean -70.0000 %
Accommodation Rate to Steady State -0.1262 %/ms
Accommodation at Steady State Mean -107.2258 %
Accommodation Rate Mean at Steady State 274.5557 ms
ISI CV 1.0400
ISI Median 75.5650 ms
ISI Burst Mean Change 13.0400 %
Spike Rate (Strong Stimulation) 24.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 9.3000 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 17.4200 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 8.0800 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2209.3300 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 3572.61 µm2
Number of Stems 6.0
Number of Bifurcations 25.0
Number of Branches 56.0
Overall Width 151.934 µm
Overall Height 441.12 µm
Overall Depth 33.48 µm
Average Diameter 0.45543 µm
Total Length 2344.73 µm
Total Surface 3653.67 µm2
Total Volume 1369.78 µm3
Max Euclidean Distance 358.584 µm
Max Path Distance 399.517 µm
Max Branch Order 9.0
Average Contraction 0.918945
Total Fragmentation 1973.0
Partition Asymmetry 0.526667
Average Rall's Ratio 2.34
Average Bifurcation Angle Local 59.5267 °
Average Bifurcation Angle Remote 64.6192 °
Fractal Dimension 1.02472
Complexity Summary
State Equations 131
Optimal Time-Step 0.01226 ms
Relative Complexity 13.31 HH
Model Size
Sections 55
Compartments 115
State Equations 131
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.01226 ms
Optimal Time-Step Error 1.99 %
Optimal Time-Step Benchmark Run Time 13.31 HH
 
Maximum Stable Time-Step 0.125 ms
Maximum Stable Time-Step Error 3.09 %
Max. Stable Time-Step Benchmark Run Time 20.39 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 12570 Hz
CVODE Steps Per AP 580
CVODE Benchmark Run Time 19.71 HH
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