Primary visual area layer 4 spiny 422738880 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Nr5a1-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001521
Cell_480633088.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001521
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Regular Spikers (RS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -92.77 mV
Rheobase Current Interval (0.09613, 0.09888] nA
Threshold Current Interval (0.64453, 0.70312] nA
Bias Current (to -80.00 mV) 0.0418 nA
Testing Temperature 34.0 °C
Stability Interval [-3.75, 15.0] nA
AP 1-2 Amplitude Drop 0.3205 mV
AP 1 Steady State Amplitude Change 0.3834 mV
AP 1 Amplitude 77.1812 mV
AP 1 Width at Half Height 0.3500 ms
AP 1 Width (Peak To Trough) 2.5000 ms
AP 1 Rate of Change Peak to Trough -34.0182 mV/ms
AP 1 AHP Depth 7.8644 mV
AP2 Amplitude 76.8607 mV
AP2 Width at Half Height 0.3600 ms
AP 2 Width (Peak to Trough) 15.2000 ms
AP 2 Rate of Change Peak to Trough -5.7953 mV/ms
AP 2 AHP Depth 11.2282 mV
AP 1-2 Amplitude Change Percent -0.4152 %
AP 1-2 Half Width Change Percent 2.8571 %
AP 1-2 Rate of Change Peak to Trough Percent Change -82.9641 %
AP 1-2 AHP Depth Percent Change 42.7734 %
Input Resistance 393.0944 MΩ
AP 1 Delay Mean 36.1400 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 45.8100 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 23.3600 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -55.5556 %
Steady State Accommodation Mean -55.5556 %
Accommodation Rate to Steady State -0.0924 %/ms
Accommodation at Steady State Mean -91.7455 %
Accommodation Rate Mean at Steady State 282.7261 ms
ISI CV 2.5246
ISI Median 108.9900 ms
ISI Burst Mean Change 283.1437 %
Spike Rate (Strong Stimulation) 30.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 11.3700 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 15.6300 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 4.0500 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2041.6200 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 6608.28 µm2
Number of Stems 6.0
Number of Bifurcations 25.0
Number of Branches 56.0
Overall Width 360.32 µm
Overall Height 220.667 µm
Overall Depth 89.18 µm
Average Diameter 0.389818 µm
Total Length 2623.79 µm
Total Surface 3704.19 µm2
Total Volume 2015.75 µm3
Max Euclidean Distance 334.621 µm
Max Path Distance 352.572 µm
Max Branch Order 5.0
Average Contraction 0.905542
Total Fragmentation 2125.0
Partition Asymmetry 0.449905
Average Rall's Ratio 2.44812
Average Bifurcation Angle Local 70.1971 °
Average Bifurcation Angle Remote 57.6295 °
Fractal Dimension 1.02836
Complexity Summary
State Equations 166
Optimal Time-Step 0.02408 ms
Relative Complexity 12.14 HH
Model Size
Sections 56
Compartments 138
State Equations 166
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02408 ms
Optimal Time-Step Error 1.17 %
Optimal Time-Step Benchmark Run Time 12.14 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 2.30 %
Max. Stable Time-Step Benchmark Run Time 9.13 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 4172 Hz
CVODE Steps Per AP 1365
CVODE Benchmark Run Time 34.26 HH
Website & Images Copyright NeuroML © 2019 For questions: Contact us Links: Search Test |  ModelDB WS