Primary visual area layer 5 spiny 486111903 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Rbp4-Cre_KL100
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001519
Cell_486556811.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001519
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Accommodating Wide AP Multi-Spikers (awMS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -83.89 mV
Rheobase Current Interval (0.17830, 0.18265] nA
Threshold Current Interval (1.05469, 1.11328] nA
Bias Current (to -70.00 mV) 0.1009 nA
Testing Temperature 34.0 °C
Stability Interval [-2.1875, 15.0] nA
AP 1-2 Amplitude Drop 4.7774 mV
AP 1 Steady State Amplitude Change 4.8803 mV
AP 1 Amplitude 78.2857 mV
AP 1 Width at Half Height 0.7600 ms
AP 1 Width (Peak To Trough) 14.2200 ms
AP 1 Rate of Change Peak to Trough -6.2613 mV/ms
AP 1 AHP Depth 10.7496 mV
AP2 Amplitude 73.5083 mV
AP2 Width at Half Height 0.7700 ms
AP 2 Width (Peak to Trough) 13.2700 ms
AP 2 Rate of Change Peak to Trough -6.7005 mV/ms
AP 2 AHP Depth 15.4075 mV
AP 1-2 Amplitude Change Percent -6.1025 %
AP 1-2 Half Width Change Percent 1.3158 %
AP 1-2 Rate of Change Peak to Trough Percent Change 7.0151 %
AP 1-2 AHP Depth Percent Change 43.3305 %
Input Resistance 73.9860 MΩ
AP 1 Delay Mean 28.1100 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 69.8900 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 59.0300 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean -20.0000 %
Accommodation Rate to Steady State -0.0807 %/ms
Accommodation at Steady State Mean -53.6908 %
Accommodation Rate Mean at Steady State 45.6831 ms
ISI CV 7.5816
ISI Median 86.5050 ms
ISI Burst Mean Change 82.5754 %
Spike Rate (Strong Stimulation) 30.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 7.9900 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 18.2900 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 17.0150 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2181.6700 ms
Frequency Filter Type High-Pass
Frequency Filter Pass Above 47.1776 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 15076.6 µm2
Number of Stems 10.0
Number of Bifurcations 52.0
Number of Branches 114.0
Overall Width 184.762 µm
Overall Height 724.307 µm
Overall Depth 96.94 µm
Average Diameter 0.524679 µm
Total Length 4861.69 µm
Total Surface 8825.24 µm2
Total Volume 5056.31 µm3
Max Euclidean Distance 649.584 µm
Max Path Distance 763.08 µm
Max Branch Order 22.0
Average Contraction 0.914361
Total Fragmentation 4001.0
Partition Asymmetry 0.558253
Average Rall's Ratio 2.1665
Average Bifurcation Angle Local 78.8418 °
Average Bifurcation Angle Remote 68.8011 °
Fractal Dimension 1.02538
Complexity Summary
State Equations 266
Optimal Time-Step 0.00778 ms
Relative Complexity 39.18 HH
Model Size
Sections 114
Compartments 250
State Equations 266
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00778 ms
Optimal Time-Step Error 0.18 %
Optimal Time-Step Benchmark Run Time 39.18 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 1.84 %
Max. Stable Time-Step Benchmark Run Time 76.18 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 11832 Hz
CVODE Steps Per AP 963
CVODE Benchmark Run Time 43.02 HH
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