Primary visual area layer 5 aspiny 321023397 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Pvalb-IRES-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001517
Cell_496930338.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001517
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Fast Spikers (FS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -88.41 mV
Rheobase Current Interval (0.17029, 0.17303] nA
Threshold Current Interval (0.64453, 0.70312] nA
Bias Current (to -80.00 mV) 0.0381 nA
Testing Temperature 34.0 °C
Stability Interval [-4.0625, 15.0] nA
AP 1-2 Amplitude Drop -1.3188 mV
AP 1 Steady State Amplitude Change -1.2194 mV
AP 1 Amplitude 47.8541 mV
AP 1 Width at Half Height 0.3400 ms
AP 1 Width (Peak To Trough) 2.1500 ms
AP 1 Rate of Change Peak to Trough -30.7265 mV/ms
AP 1 AHP Depth 18.2079 mV
AP2 Amplitude 49.1729 mV
AP2 Width at Half Height 0.3500 ms
AP 2 Width (Peak to Trough) 2.2100 ms
AP 2 Rate of Change Peak to Trough -31.2347 mV/ms
AP 2 AHP Depth 19.8557 mV
AP 1-2 Amplitude Change Percent 2.7559 %
AP 1-2 Half Width Change Percent 2.9412 %
AP 1-2 Rate of Change Peak to Trough Percent Change 1.6536 %
AP 1-2 AHP Depth Percent Change 9.0494 %
Input Resistance 225.7491 MΩ
AP 1 Delay Mean 16.6300 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 29.5300 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 14.2550 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 4.5455 %
Steady State Accommodation Mean 9.0909 %
Accommodation Rate to Steady State 0.1451 %/ms
Accommodation at Steady State Mean -25.9299 %
Accommodation Rate Mean at Steady State 0.2672 ms
ISI CV 30.9688
ISI Median 17.3150 ms
ISI Burst Mean Change 21.0078 %
Spike Rate (Strong Stimulation) 127.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 4.4000 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 10.2100 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 5.8750 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2031.4800 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 4563.15 µm2
Number of Stems 6.0
Number of Bifurcations 11.0
Number of Branches 28.0
Overall Width 198.194 µm
Overall Height 292.309 µm
Overall Depth 68.99 µm
Average Diameter 0.467672 µm
Total Length 1698.14 µm
Total Surface 2890.74 µm2
Total Volume 1547.93 µm3
Max Euclidean Distance 212.328 µm
Max Path Distance 243.255 µm
Max Branch Order 3.0
Average Contraction 0.926138
Total Fragmentation 1368.0
Partition Asymmetry 0.545455
Average Rall's Ratio 2.14
Average Bifurcation Angle Local 87.2135 °
Average Bifurcation Angle Remote 64.1359 °
Fractal Dimension 1.01944
Complexity Summary
State Equations 116
Optimal Time-Step 0.02389 ms
Relative Complexity 9.62 HH
Model Size
Sections 28
Compartments 88
State Equations 116
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02389 ms
Optimal Time-Step Error 2.12 %
Optimal Time-Step Benchmark Run Time 9.62 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 3.48 %
Max. Stable Time-Step Benchmark Run Time 7.18 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 6305 Hz
CVODE Steps Per AP 1106
CVODE Benchmark Run Time 26.26 HH
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