Primary visual area layer 2/3 aspiny 324493977 Cell

Model Type:
Cell
Neurolex IDs: Visual cortex primary layer 2
Visual cortex primary layer 3
Keywords: Mus musculus, Sst-IRES-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001513
Cell_472304676.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001513
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Non-accommodating Regular Spikers (naRS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -86.05 mV
Rheobase Current Interval (0.13390, 0.13687] nA
Threshold Current Interval (0.70312, 0.76172] nA
Bias Current (to -80.00 mV) 0.0404 nA
Testing Temperature 34.0 °C
Stability Interval [-5.3125, 15.0] nA
AP 1-2 Amplitude Drop 0.6773 mV
AP 1 Steady State Amplitude Change 0.5723 mV
AP 1 Amplitude 53.7152 mV
AP 1 Width at Half Height 0.4600 ms
AP 1 Width (Peak To Trough) 3.2800 ms
AP 1 Rate of Change Peak to Trough -19.8126 mV/ms
AP 1 AHP Depth 11.2703 mV
AP2 Amplitude 53.0379 mV
AP2 Width at Half Height 0.4600 ms
AP 2 Width (Peak to Trough) 6.2400 ms
AP 2 Rate of Change Peak to Trough -10.7763 mV/ms
AP 2 AHP Depth 14.2060 mV
AP 1-2 Amplitude Change Percent -1.2609 %
AP 1-2 Half Width Change Percent 0.0000 %
AP 1-2 Rate of Change Peak to Trough Percent Change -45.6091 %
AP 1-2 AHP Depth Percent Change 26.0484 %
Input Resistance 152.4777 MΩ
AP 1 Delay Mean 23.6600 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 38.3500 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 24.1350 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 7.6923 %
Steady State Accommodation Mean 15.3846 %
Accommodation Rate to Steady State 0.2139 %/ms
Accommodation at Steady State Mean -48.7623 %
Accommodation Rate Mean at Steady State 0.0342 ms
ISI CV 13.4096
ISI Median 28.1800 ms
ISI Burst Mean Change 128.5909 %
Spike Rate (Strong Stimulation) 1.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 7.2700 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 12.8600 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) N/A ms
Burst 1 ISI SD (Strong Stimulation) N/A ms
Ramp First Spike Time 2050.8800 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 6395.94 µm2
Number of Stems 7.0
Number of Bifurcations 31.0
Number of Branches 69.0
Overall Width 217.7 µm
Overall Height 274.06 µm
Overall Depth 52.26 µm
Average Diameter 0.399256 µm
Total Length 3724.57 µm
Total Surface 5129.23 µm2
Total Volume 2117.82 µm3
Max Euclidean Distance 202.806 µm
Max Path Distance 275.185 µm
Max Branch Order 7.0
Average Contraction 0.836479
Total Fragmentation 2980.0
Partition Asymmetry 0.476703
Average Rall's Ratio 2.35
Average Bifurcation Angle Local 86.6534 °
Average Bifurcation Angle Remote 67.1831 °
Fractal Dimension 1.061
Complexity Summary
State Equations 213
Optimal Time-Step 0.02221 ms
Relative Complexity 15.25 HH
Model Size
Sections 69
Compartments 185
State Equations 213
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02221 ms
Optimal Time-Step Error 0.89 %
Optimal Time-Step Benchmark Run Time 15.25 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 2.63 %
Max. Stable Time-Step Benchmark Run Time 10.58 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 4414 Hz
CVODE Steps Per AP 1244
CVODE Benchmark Run Time 37.53 HH
Website & Images Copyright NeuroML © 2019 For questions: Contact us Links: Search Test |  ModelDB WS