Primary visual area layer 4 spiny 479728896 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Rbp4-Cre_KL100
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001508
Cell_482525598.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001508
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Fast Spikers (FS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -97.24 mV
Rheobase Current Interval (0.09155, 0.09521] nA
Threshold Current Interval (0.87891, 0.93750] nA
Bias Current (to -80.00 mV) 0.0783 nA
Testing Temperature 34.0 °C
Stability Interval [-2.8125, 15.0] nA
AP 1-2 Amplitude Drop 2.6090 mV
AP 1 Steady State Amplitude Change 3.4680 mV
AP 1 Amplitude 76.9343 mV
AP 1 Width at Half Height 0.6500 ms
AP 1 Width (Peak To Trough) 2.7000 ms
AP 1 Rate of Change Peak to Trough -34.8027 mV/ms
AP 1 AHP Depth 17.0329 mV
AP2 Amplitude 74.3253 mV
AP2 Width at Half Height 0.6600 ms
AP 2 Width (Peak to Trough) 2.8500 ms
AP 2 Rate of Change Peak to Trough -32.4062 mV/ms
AP 2 AHP Depth 18.0323 mV
AP 1-2 Amplitude Change Percent -3.3911 %
AP 1-2 Half Width Change Percent 1.5385 %
AP 1-2 Rate of Change Peak to Trough Percent Change -6.8859 %
AP 1-2 AHP Depth Percent Change 5.8677 %
Input Resistance 205.6688 MΩ
AP 1 Delay Mean 50.4400 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 79.2500 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 30.7600 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean 0.0000 %
Accommodation Rate to Steady State 0.0000 %/ms
Accommodation at Steady State Mean -19.1777 %
Accommodation Rate Mean at Steady State 592.6779 ms
ISI CV 16.9617
ISI Median 38.7000 ms
ISI Burst Mean Change 13.5370 %
Spike Rate (Strong Stimulation) 89.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 15.9000 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 26.0900 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 10.2150 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2076.9400 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 7094.55 µm2
Number of Stems 6.0
Number of Bifurcations 24.0
Number of Branches 54.0
Overall Width 219.11 µm
Overall Height 371.103 µm
Overall Depth 72.01 µm
Average Diameter 0.465303 µm
Total Length 3000.48 µm
Total Surface 4838.93 µm2
Total Volume 2367.13 µm3
Max Euclidean Distance 443.484 µm
Max Path Distance 471.178 µm
Max Branch Order 6.0
Average Contraction 0.89929
Total Fragmentation 2532.0
Partition Asymmetry 0.5
Average Rall's Ratio 1.58687
Average Bifurcation Angle Local 62.5452 °
Average Bifurcation Angle Remote 61.1287 °
Fractal Dimension 1.03189
Complexity Summary
State Equations 173
Optimal Time-Step 0.00812 ms
Relative Complexity 23.01 HH
Model Size
Sections 53
Compartments 157
State Equations 173
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00812 ms
Optimal Time-Step Error 0.92 %
Optimal Time-Step Benchmark Run Time 23.01 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 1.65 %
Max. Stable Time-Step Benchmark Run Time 46.69 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 16277 Hz
CVODE Steps Per AP 451
CVODE Benchmark Run Time 25.53 HH
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