Primary visual area layer 4 spiny 476457450 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Nr5a1-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001507
Cell_477876583.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001507
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Regular Spikers (RS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -89.23 mV
Rheobase Current Interval (0.05722, 0.05951] nA
Threshold Current Interval (0.52734, 0.58594] nA
Bias Current (to -80.00 mV) 0.0248 nA
Testing Temperature 34.0 °C
Stability Interval [-1.875, 15.0] nA
AP 1-2 Amplitude Drop 1.5640 mV
AP 1 Steady State Amplitude Change 2.6448 mV
AP 1 Amplitude 70.4937 mV
AP 1 Width at Half Height 0.6600 ms
AP 1 Width (Peak To Trough) 3.4600 ms
AP 1 Rate of Change Peak to Trough -24.2855 mV/ms
AP 1 AHP Depth 13.5340 mV
AP2 Amplitude 68.9297 mV
AP2 Width at Half Height 0.6900 ms
AP 2 Width (Peak to Trough) 4.0400 ms
AP 2 Rate of Change Peak to Trough -20.1853 mV/ms
AP 2 AHP Depth 12.6189 mV
AP 1-2 Amplitude Change Percent -2.2187 %
AP 1-2 Half Width Change Percent 4.5455 %
AP 1-2 Rate of Change Peak to Trough Percent Change -16.8832 %
AP 1-2 AHP Depth Percent Change -6.7613 %
Input Resistance 370.3983 MΩ
AP 1 Delay Mean 65.1900 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 86.7700 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 28.5500 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean 0.0000 %
Accommodation Rate to Steady State 0.0000 %/ms
Accommodation at Steady State Mean -80.5114 %
Accommodation Rate Mean at Steady State 50.4312 ms
ISI CV 4.6888
ISI Median 79.2550 ms
ISI Burst Mean Change 64.5968 %
Spike Rate (Strong Stimulation) 45.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 19.9500 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 30.6600 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 12.3950 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2097.9900 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 4921.31 µm2
Number of Stems 5.0
Number of Bifurcations 27.0
Number of Branches 59.0
Overall Width 344.061 µm
Overall Height 226.962 µm
Overall Depth 64.65 µm
Average Diameter 0.483874 µm
Total Length 3020.5 µm
Total Surface 5019.2 µm2
Total Volume 1899.12 µm3
Max Euclidean Distance 410.308 µm
Max Path Distance 439.169 µm
Max Branch Order 6.0
Average Contraction 0.890136
Total Fragmentation 2784.0
Partition Asymmetry 0.39632
Average Rall's Ratio 1.485
Average Bifurcation Angle Local 65.3956 °
Average Bifurcation Angle Remote 56.1166 °
Fractal Dimension 1.03679
Complexity Summary
State Equations 177
Optimal Time-Step 0.01161 ms
Relative Complexity 16.32 HH
Model Size
Sections 59
Compartments 161
State Equations 177
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.01161 ms
Optimal Time-Step Error 0.49 %
Optimal Time-Step Benchmark Run Time 16.32 HH
 
Maximum Stable Time-Step 0.125 ms
Maximum Stable Time-Step Error 1.59 %
Max. Stable Time-Step Benchmark Run Time 23.68 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 12460 Hz
CVODE Steps Per AP 1073
CVODE Benchmark Run Time 28.89 HH
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