Primary visual area layer 4 spiny 479704527 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Rbp4-Cre_KL100
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001504
Cell_483108201.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001504
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Accommodating Wide AP Multi-Spikers (awMS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -88.18 mV
Rheobase Current Interval (0.16342, 0.16823] nA
Threshold Current Interval (1.17188, 1.23047] nA
Bias Current (to -80.00 mV) 0.0758 nA
Testing Temperature 34.0 °C
Stability Interval [-4.375, 15.0] nA
AP 1-2 Amplitude Drop 1.9308 mV
AP 1 Steady State Amplitude Change 10.9810 mV
AP 1 Amplitude 52.1557 mV
AP 1 Width at Half Height 1.1200 ms
AP 1 Width (Peak To Trough) 13.7800 ms
AP 1 Rate of Change Peak to Trough -5.0499 mV/ms
AP 1 AHP Depth 17.4316 mV
AP2 Amplitude 50.2250 mV
AP2 Width at Half Height 1.1200 ms
AP 2 Width (Peak to Trough) 14.0900 ms
AP 2 Rate of Change Peak to Trough -4.8548 mV/ms
AP 2 AHP Depth 18.1787 mV
AP 1-2 Amplitude Change Percent -3.7019 %
AP 1-2 Half Width Change Percent 0.0000 %
AP 1-2 Rate of Change Peak to Trough Percent Change -3.8637 %
AP 1-2 AHP Depth Percent Change 4.2858 %
Input Resistance 104.1150 MΩ
AP 1 Delay Mean 38.5700 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 70.3900 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 32.2250 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -50.0000 %
Steady State Accommodation Mean -50.0000 %
Accommodation Rate to Steady State -0.0991 %/ms
Accommodation at Steady State Mean -84.2964 %
Accommodation Rate Mean at Steady State 229.5880 ms
ISI CV 2.8962
ISI Median 106.4200 ms
ISI Burst Mean Change 2.5456 %
Spike Rate (Strong Stimulation) 31.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 11.6300 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 28.9600 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 18.8400 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2058.0100 ms
Frequency Filter Type Low-Pass
Frequency Filter Pass Below 113.4989 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 5823.11 µm2
Number of Stems 11.0
Number of Bifurcations 51.0
Number of Branches 113.0
Overall Width 228.947 µm
Overall Height 595.327 µm
Overall Depth 67.93 µm
Average Diameter 0.351807 µm
Total Length 5630.98 µm
Total Surface 6645.31 µm2
Total Volume 2058.63 µm3
Max Euclidean Distance 518.185 µm
Max Path Distance 577.225 µm
Max Branch Order 7.0
Average Contraction 0.892263
Total Fragmentation 4673.0
Partition Asymmetry 0.52589
Average Rall's Ratio 3.0175
Average Bifurcation Angle Local 64.4929 °
Average Bifurcation Angle Remote 53.7812 °
Fractal Dimension 1.02964
Complexity Summary
State Equations 301
Optimal Time-Step 0.01099 ms
Relative Complexity 29.48 HH
Model Size
Sections 113
Compartments 285
State Equations 301
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.01099 ms
Optimal Time-Step Error 0.75 %
Optimal Time-Step Benchmark Run Time 29.48 HH
 
Maximum Stable Time-Step 0.125 ms
Maximum Stable Time-Step Error 3.91 %
Max. Stable Time-Step Benchmark Run Time 40.50 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 12537 Hz
CVODE Steps Per AP 1336
CVODE Benchmark Run Time 55.18 HH
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