Primary visual area layer 4 spiny 320207387 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Scnn1a-Tg3-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001502
Cell_329321704.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001502
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Fast Spikers (FS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -80.75 mV
Rheobase Current Interval (0.21973, 0.22247] nA
Threshold Current Interval (0.64453, 0.70312] nA
Bias Current (to -70.00 mV) 0.1333 nA
Testing Temperature 34.0 °C
Stability Interval [-3.4375, 15.0] nA
AP 1-2 Amplitude Drop 14.6030 mV
AP 1 Steady State Amplitude Change 16.1018 mV
AP 1 Amplitude 76.2158 mV
AP 1 Width at Half Height 0.6400 ms
AP 1 Width (Peak To Trough) 4.4700 ms
AP 1 Rate of Change Peak to Trough -20.9251 mV/ms
AP 1 AHP Depth 17.3194 mV
AP2 Amplitude 61.6128 mV
AP2 Width at Half Height 0.7100 ms
AP 2 Width (Peak to Trough) 7.2800 ms
AP 2 Rate of Change Peak to Trough -10.7348 mV/ms
AP 2 AHP Depth 16.5364 mV
AP 1-2 Amplitude Change Percent -19.1601 %
AP 1-2 Half Width Change Percent 10.9375 %
AP 1-2 Rate of Change Peak to Trough Percent Change -48.6990 %
AP 1-2 AHP Depth Percent Change -4.5209 %
Input Resistance 72.1068 MΩ
AP 1 Delay Mean 10.2000 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 44.6400 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 34.9550 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean -9.0909 %
Accommodation Rate to Steady State -0.0074 %/ms
Accommodation at Steady State Mean -99.9423 %
Accommodation Rate Mean at Steady State 18622831.3209 ms
ISI CV 20.4322
ISI Median 37.8950 ms
ISI Burst Mean Change 2.9907 %
Spike Rate (Strong Stimulation) 109.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 2.7000 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 11.8600 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 9.1300 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2022.9700 ms
Frequency Filter Type High-Pass
Frequency Filter Pass Above 72.2767 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 10694.9 µm2
Number of Stems 7.0
Number of Bifurcations 44.0
Number of Branches 95.0
Overall Width 221.155 µm
Overall Height 630.421 µm
Overall Depth 54.15 µm
Average Diameter 0.516197 µm
Total Length 4331.14 µm
Total Surface 7613.16 µm2
Total Volume 3636.33 µm3
Max Euclidean Distance 542.048 µm
Max Path Distance 696.602 µm
Max Branch Order 11.0
Average Contraction 0.838484
Total Fragmentation 3425.0
Partition Asymmetry 0.410591
Average Rall's Ratio 2.52235
Average Bifurcation Angle Local 72.2409 °
Average Bifurcation Angle Remote 61.0837 °
Fractal Dimension 1.06299
Complexity Summary
State Equations 243
Optimal Time-Step 0.01104 ms
Relative Complexity 24.10 HH
Model Size
Sections 95
Compartments 227
State Equations 243
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.01104 ms
Optimal Time-Step Error 0.11 %
Optimal Time-Step Benchmark Run Time 24.10 HH
 
Maximum Stable Time-Step 0.125 ms
Maximum Stable Time-Step Error 1.01 %
Max. Stable Time-Step Benchmark Run Time 33.24 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 12276 Hz
CVODE Steps Per AP 833
CVODE Benchmark Run Time 36.05 HH
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