Primary visual area layer 5 spiny 485574832 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Rbp4-Cre_KL100
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001501
Cell_486052412.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001501
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Non-accommodating Regular Spikers (naRS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -86.34 mV
Rheobase Current Interval (0.18127, 0.18631] nA
Threshold Current Interval (1.23047, 1.28906] nA
Bias Current (to -80.00 mV) 0.0665 nA
Testing Temperature 34.0 °C
Stability Interval [-9.6875, 15.0] nA
AP 1-2 Amplitude Drop -0.0019 mV
AP 1 Steady State Amplitude Change -0.4897 mV
AP 1 Amplitude 79.1280 mV
AP 1 Width at Half Height 0.4800 ms
AP 1 Width (Peak To Trough) 24.2600 ms
AP 1 Rate of Change Peak to Trough -4.0541 mV/ms
AP 1 AHP Depth 19.2239 mV
AP2 Amplitude 79.1299 mV
AP2 Width at Half Height 0.5000 ms
AP 2 Width (Peak to Trough) 21.4100 ms
AP 2 Rate of Change Peak to Trough -4.4856 mV/ms
AP 2 AHP Depth 16.9068 mV
AP 1-2 Amplitude Change Percent 0.0024 %
AP 1-2 Half Width Change Percent 4.1667 %
AP 1-2 Rate of Change Peak to Trough Percent Change 10.6441 %
AP 1-2 AHP Depth Percent Change -12.0533 %
Input Resistance 96.0094 MΩ
AP 1 Delay Mean 34.4700 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 138.5400 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 92.4300 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean 0.0000 %
Accommodation Rate to Steady State 0.0000 %/ms
Accommodation at Steady State Mean -0.0000 %
Accommodation Rate Mean at Steady State 6.7306 ms
ISI CV 13.5908
ISI Median 75.4800 ms
ISI Burst Mean Change -22.3696 %
Spike Rate (Strong Stimulation) 22.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 9.2300 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 100.2500 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 79.6950 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2112.7800 ms
Frequency Filter Type High-Pass
Frequency Filter Pass Above 104.5352 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 5476.95 µm2
Number of Stems 10.0
Number of Bifurcations 45.0
Number of Branches 100.0
Overall Width 264.959 µm
Overall Height 638.55 µm
Overall Depth 97.9 µm
Average Diameter 0.477364 µm
Total Length 4238.8 µm
Total Surface 6855.84 µm2
Total Volume 2351.91 µm3
Max Euclidean Distance 575.612 µm
Max Path Distance 753.599 µm
Max Branch Order 18.0
Average Contraction 0.890022
Total Fragmentation 3500.0
Partition Asymmetry 0.586423
Average Rall's Ratio 2.02417
Average Bifurcation Angle Local 74.0454 °
Average Bifurcation Angle Remote 79.2449 °
Fractal Dimension 1.03036
Complexity Summary
State Equations 254
Optimal Time-Step 0.02162 ms
Relative Complexity 18.50 HH
Model Size
Sections 100
Compartments 226
State Equations 254
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02162 ms
Optimal Time-Step Error 0.74 %
Optimal Time-Step Benchmark Run Time 18.50 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 3.45 %
Max. Stable Time-Step Benchmark Run Time 12.49 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 3615 Hz
CVODE Steps Per AP 1662
CVODE Benchmark Run Time 53.19 HH
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