posteromedial visual area layer 4 spiny 321906005 Cell

Model Type:
Cell
Neurolex IDs: Posteromedial visual area layer 4
Keywords: Mus musculus, Nr5a1-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001500
Cell_473834758.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001500
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Non-accommodating Regular Spikers (naRS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -96.39 mV
Rheobase Current Interval (0.10986, 0.11330] nA
Threshold Current Interval (0.82031, 0.87891] nA
Bias Current (to -80.00 mV) 0.0512 nA
Testing Temperature 34.0 °C
Stability Interval [-2.1875, 15.0] nA
AP 1-2 Amplitude Drop 8.1963 mV
AP 1 Steady State Amplitude Change 8.4999 mV
AP 1 Amplitude 67.5374 mV
AP 1 Width at Half Height 0.5800 ms
AP 1 Width (Peak To Trough) 11.4800 ms
AP 1 Rate of Change Peak to Trough -7.3097 mV/ms
AP 1 AHP Depth 16.3775 mV
AP2 Amplitude 59.3411 mV
AP2 Width at Half Height 0.6300 ms
AP 2 Width (Peak to Trough) 14.4100 ms
AP 2 Rate of Change Peak to Trough -5.2643 mV/ms
AP 2 AHP Depth 16.5172 mV
AP 1-2 Amplitude Change Percent -12.1360 %
AP 1-2 Half Width Change Percent 8.6207 %
AP 1-2 Rate of Change Peak to Trough Percent Change -27.9819 %
AP 1-2 AHP Depth Percent Change 0.8525 %
Input Resistance 329.4497 MΩ
AP 1 Delay Mean 37.7100 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 179.7000 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 133.9650 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 33.3333 %
Steady State Accommodation Mean 33.3333 %
Accommodation Rate to Steady State 0.1855 %/ms
Accommodation at Steady State Mean -0.0031 %
Accommodation Rate Mean at Steady State 2915035.4498 ms
ISI CV 13.9664
ISI Median 111.1300 ms
ISI Burst Mean Change -11.3036 %
Spike Rate (Strong Stimulation) 80.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 11.6400 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 24.9000 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 13.4050 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2064.5400 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 4546.73 µm2
Number of Stems 5.0
Number of Bifurcations 22.0
Number of Branches 49.0
Overall Width 171.837 µm
Overall Height 273.262 µm
Overall Depth 86.72 µm
Average Diameter 0.290445 µm
Total Length 2430.32 µm
Total Surface 2590.66 µm2
Total Volume 1330.29 µm3
Max Euclidean Distance 327.497 µm
Max Path Distance 364.444 µm
Max Branch Order 6.0
Average Contraction 0.904835
Total Fragmentation 1864.0
Partition Asymmetry 0.54697
Average Rall's Ratio 2.12
Average Bifurcation Angle Local 79.8604 °
Average Bifurcation Angle Remote 61.1374 °
Fractal Dimension 1.02767
Complexity Summary
State Equations 142
Optimal Time-Step 0.00785 ms
Relative Complexity 21.05 HH
Model Size
Sections 48
Compartments 126
State Equations 142
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00785 ms
Optimal Time-Step Error 0.25 %
Optimal Time-Step Benchmark Run Time 21.05 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 0.83 %
Max. Stable Time-Step Benchmark Run Time 41.30 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 13119 Hz
CVODE Steps Per AP 766
CVODE Benchmark Run Time 22.58 HH
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