Primary visual area layer 2/3 aspiny 327962063 Cell

Model Type:
Cell
Neurolex IDs: Visual cortex primary layer 2
Visual cortex primary layer 3
Keywords: Mus musculus, Htr3a-Cre_NO152
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001499
Cell_472352327.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001499
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Regular Spikers (RS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -86.86 mV
Rheobase Current Interval (0.03044, 0.03204] nA
Threshold Current Interval (0.35156, 0.41016] nA
Bias Current (to -80.00 mV) 0.0119 nA
Testing Temperature 34.0 °C
Stability Interval [-1.25, 15.0] nA
AP 1-2 Amplitude Drop 0.0356 mV
AP 1 Steady State Amplitude Change 4.1228 mV
AP 1 Amplitude 56.0030 mV
AP 1 Width at Half Height 0.7100 ms
AP 1 Width (Peak To Trough) 3.0200 ms
AP 1 Rate of Change Peak to Trough -25.1909 mV/ms
AP 1 AHP Depth 20.0734 mV
AP2 Amplitude 55.9674 mV
AP2 Width at Half Height 0.7200 ms
AP 2 Width (Peak to Trough) 3.0600 ms
AP 2 Rate of Change Peak to Trough -24.6247 mV/ms
AP 2 AHP Depth 19.3842 mV
AP 1-2 Amplitude Change Percent -0.0636 %
AP 1-2 Half Width Change Percent 1.4085 %
AP 1-2 Rate of Change Peak to Trough Percent Change -2.2475 %
AP 1-2 AHP Depth Percent Change -3.4333 %
Input Resistance 539.6443 MΩ
AP 1 Delay Mean 71.9400 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 94.7800 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 23.3200 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -33.3333 %
Steady State Accommodation Mean -50.0000 %
Accommodation Rate to Steady State -0.1208 %/ms
Accommodation at Steady State Mean -93.0396 %
Accommodation Rate Mean at Steady State 131.1676 ms
ISI CV 2.6975
ISI Median 104.3600 ms
ISI Burst Mean Change 4.2032 %
Spike Rate (Strong Stimulation) 38.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 23.4200 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 36.1900 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 12.7600 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2089.2500 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 3284.51 µm2
Number of Stems 4.0
Number of Bifurcations 21.0
Number of Branches 46.0
Overall Width 161.018 µm
Overall Height 373.936 µm
Overall Depth 71.0 µm
Average Diameter 0.381778 µm
Total Length 2155.91 µm
Total Surface 2890.97 µm2
Total Volume 1102.47 µm3
Max Euclidean Distance 262.302 µm
Max Path Distance 309.139 µm
Max Branch Order 5.0
Average Contraction 0.90291
Total Fragmentation 1795.0
Partition Asymmetry 0.505051
Average Rall's Ratio 2.348
Average Bifurcation Angle Local 72.1355 °
Average Bifurcation Angle Remote 68.8619 °
Fractal Dimension 1.02871
Complexity Summary
State Equations 122
Optimal Time-Step 0.01071 ms
Relative Complexity 13.53 HH
Model Size
Sections 46
Compartments 106
State Equations 122
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.01071 ms
Optimal Time-Step Error 0.44 %
Optimal Time-Step Benchmark Run Time 13.53 HH
 
Maximum Stable Time-Step 0.125 ms
Maximum Stable Time-Step Error 2.74 %
Max. Stable Time-Step Benchmark Run Time 18.11 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 13521 Hz
CVODE Steps Per AP 357
CVODE Benchmark Run Time 16.28 HH
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