Primary visual area layer 5 spiny 354190013 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Scnn1a-Tg2-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001497
Cell_472306460.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001497
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Accommodating Wide AP Multi-Spikers (awMS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -86.30 mV
Rheobase Current Interval (0.13184, 0.13733] nA
Threshold Current Interval (1.34766, 1.40625] nA
Bias Current (to -80.00 mV) 0.0379 nA
Testing Temperature 34.0 °C
Stability Interval [-5.3125, 15.0] nA
AP 1-2 Amplitude Drop 1.8272 mV
AP 1 Steady State Amplitude Change 5.0763 mV
AP 1 Amplitude 60.7050 mV
AP 1 Width at Half Height 0.7600 ms
AP 1 Width (Peak To Trough) 12.1700 ms
AP 1 Rate of Change Peak to Trough -6.1797 mV/ms
AP 1 AHP Depth 14.5019 mV
AP2 Amplitude 58.8779 mV
AP2 Width at Half Height 0.7700 ms
AP 2 Width (Peak to Trough) 15.8300 ms
AP 2 Rate of Change Peak to Trough -4.7510 mV/ms
AP 2 AHP Depth 16.3312 mV
AP 1-2 Amplitude Change Percent -3.0099 %
AP 1-2 Half Width Change Percent 1.3158 %
AP 1-2 Rate of Change Peak to Trough Percent Change -23.1185 %
AP 1-2 AHP Depth Percent Change 12.6142 %
Input Resistance 166.4968 MΩ
AP 1 Delay Mean 44.7100 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 82.4100 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 48.5100 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -50.0000 %
Steady State Accommodation Mean -50.0000 %
Accommodation Rate to Steady State -0.1051 %/ms
Accommodation at Steady State Mean -85.8956 %
Accommodation Rate Mean at Steady State 156.5425 ms
ISI CV 3.0491
ISI Median 179.9400 ms
ISI Burst Mean Change 57.3475 %
Spike Rate (Strong Stimulation) 48.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 14.8300 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 32.3400 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 18.7250 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2070.6200 ms
Frequency Filter Type High-Pass
Frequency Filter Pass Above 40.9072 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 9722.39 µm2
Number of Stems 10.0
Number of Bifurcations 45.0
Number of Branches 100.0
Overall Width 272.957 µm
Overall Height 671.743 µm
Overall Depth 91.65 µm
Average Diameter 0.425497 µm
Total Length 6100.8 µm
Total Surface 8842.23 µm2
Total Volume 3428.83 µm3
Max Euclidean Distance 596.075 µm
Max Path Distance 670.225 µm
Max Branch Order 11.0
Average Contraction 0.873743
Total Fragmentation 5575.0
Partition Asymmetry 0.484083
Average Rall's Ratio 2.04273
Average Bifurcation Angle Local 68.8957 °
Average Bifurcation Angle Remote 64.5834 °
Fractal Dimension 1.03805
Complexity Summary
State Equations 326
Optimal Time-Step 0.01084 ms
Relative Complexity 32.81 HH
Model Size
Sections 100
Compartments 310
State Equations 326
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.01084 ms
Optimal Time-Step Error 0.29 %
Optimal Time-Step Benchmark Run Time 32.81 HH
 
Maximum Stable Time-Step 0.125 ms
Maximum Stable Time-Step Error 1.72 %
Max. Stable Time-Step Benchmark Run Time 44.47 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 11949 Hz
CVODE Steps Per AP 892
CVODE Benchmark Run Time 48.83 HH
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