Primary visual area layer 4 spiny 487601493 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Cux2-CreERT2
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001496
Cell_488461970.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001496
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Regular Spikers (RS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -87.95 mV
Rheobase Current Interval (0.11719, 0.12085] nA
Threshold Current Interval (0.87891, 0.93750] nA
Bias Current (to -80.00 mV) 0.0342 nA
Testing Temperature 34.0 °C
Stability Interval [-3.125, 15.0] nA
AP 1-2 Amplitude Drop 1.0152 mV
AP 1 Steady State Amplitude Change 3.3221 mV
AP 1 Amplitude 65.3988 mV
AP 1 Width at Half Height 0.7100 ms
AP 1 Width (Peak To Trough) 11.0400 ms
AP 1 Rate of Change Peak to Trough -7.0052 mV/ms
AP 1 AHP Depth 11.9386 mV
AP2 Amplitude 64.3836 mV
AP2 Width at Half Height 0.7300 ms
AP 2 Width (Peak to Trough) 11.0100 ms
AP 2 Rate of Change Peak to Trough -6.9774 mV/ms
AP 2 AHP Depth 12.4378 mV
AP 1-2 Amplitude Change Percent -1.5523 %
AP 1-2 Half Width Change Percent 2.8169 %
AP 1-2 Rate of Change Peak to Trough Percent Change -0.3965 %
AP 1-2 AHP Depth Percent Change 4.1816 %
Input Resistance 221.4316 MΩ
AP 1 Delay Mean 42.9700 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 74.6400 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 33.0700 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -25.0000 %
Steady State Accommodation Mean -12.5000 %
Accommodation Rate to Steady State -0.0338 %/ms
Accommodation at Steady State Mean -62.2888 %
Accommodation Rate Mean at Steady State 137.9859 ms
ISI CV 5.5986
ISI Median 65.7800 ms
ISI Burst Mean Change 8.8412 %
Spike Rate (Strong Stimulation) 28.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 12.0300 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 22.9700 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 13.6900 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2077.4400 ms
Frequency Filter Type High-Pass
Frequency Filter Pass Above 48.2356 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 6048.77 µm2
Number of Stems 10.0
Number of Bifurcations 36.0
Number of Branches 82.0
Overall Width 203.912 µm
Overall Height 577.958 µm
Overall Depth 51.99 µm
Average Diameter 0.499618 µm
Total Length 3617.71 µm
Total Surface 6135.1 µm2
Total Volume 2445.36 µm3
Max Euclidean Distance 496.783 µm
Max Path Distance 546.303 µm
Max Branch Order 9.0
Average Contraction 0.910589
Total Fragmentation 3031.0
Partition Asymmetry 0.383333
Average Rall's Ratio 2.747
Average Bifurcation Angle Local 69.95 °
Average Bifurcation Angle Remote 61.238 °
Fractal Dimension 1.02373
Complexity Summary
State Equations 196
Optimal Time-Step 0.01101 ms
Relative Complexity 20.30 HH
Model Size
Sections 82
Compartments 180
State Equations 196
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.01101 ms
Optimal Time-Step Error 0.27 %
Optimal Time-Step Benchmark Run Time 20.30 HH
 
Maximum Stable Time-Step 0.125 ms
Maximum Stable Time-Step Error 2.86 %
Max. Stable Time-Step Benchmark Run Time 27.94 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 11853 Hz
CVODE Steps Per AP 650
CVODE Benchmark Run Time 26.97 HH
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