Primary visual area layer 5 spiny 478888052 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Scnn1a-Tg2-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001495
Cell_479694721.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001495
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Accommodating Wide AP Multi-Spikers (awMS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -86.40 mV
Rheobase Current Interval (0.06592, 0.07004] nA
Threshold Current Interval (0.99609, 1.05469] nA
Bias Current (to -80.00 mV) 0.0171 nA
Testing Temperature 34.0 °C
Stability Interval [-3.75, 15.0] nA
AP 1-2 Amplitude Drop 1.5938 mV
AP 1 Steady State Amplitude Change 1.6980 mV
AP 1 Amplitude 67.6017 mV
AP 1 Width at Half Height 0.7000 ms
AP 1 Width (Peak To Trough) 20.2700 ms
AP 1 Rate of Change Peak to Trough -3.9205 mV/ms
AP 1 AHP Depth 11.8660 mV
AP2 Amplitude 66.0080 mV
AP2 Width at Half Height 0.7000 ms
AP 2 Width (Peak to Trough) 47.9500 ms
AP 2 Rate of Change Peak to Trough -1.6985 mV/ms
AP 2 AHP Depth 15.4351 mV
AP 1-2 Amplitude Change Percent -2.3576 %
AP 1-2 Half Width Change Percent 0.0000 %
AP 1-2 Rate of Change Peak to Trough Percent Change -56.6760 %
AP 1-2 AHP Depth Percent Change 30.0783 %
Input Resistance 385.0407 MΩ
AP 1 Delay Mean 95.7200 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 161.3300 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 122.3450 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -33.3333 %
Steady State Accommodation Mean 0.0000 %
Accommodation Rate to Steady State 0.0000 %/ms
Accommodation at Steady State Mean -63.6131 %
Accommodation Rate Mean at Steady State 38.5930 ms
ISI CV 5.1297
ISI Median 178.8700 ms
ISI Burst Mean Change 172.9462 %
Spike Rate (Strong Stimulation) 50.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 28.1800 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 61.9200 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 28.9850 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2117.4300 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 10541.2 µm2
Number of Stems 12.0
Number of Bifurcations 38.0
Number of Branches 88.0
Overall Width 212.73 µm
Overall Height 628.221 µm
Overall Depth 70.93 µm
Average Diameter 0.369442 µm
Total Length 4270.42 µm
Total Surface 5579.26 µm2
Total Volume 3156.96 µm3
Max Euclidean Distance 549.135 µm
Max Path Distance 614.09 µm
Max Branch Order 11.0
Average Contraction 0.931198
Total Fragmentation 3447.0
Partition Asymmetry 0.474244
Average Rall's Ratio 2.53958
Average Bifurcation Angle Local 82.4213 °
Average Bifurcation Angle Remote 60.5864 °
Fractal Dimension 1.01995
Complexity Summary
State Equations 243
Optimal Time-Step 0.01148 ms
Relative Complexity 22.89 HH
Model Size
Sections 87
Compartments 227
State Equations 243
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.01148 ms
Optimal Time-Step Error 0.55 %
Optimal Time-Step Benchmark Run Time 22.89 HH
 
Maximum Stable Time-Step 0.125 ms
Maximum Stable Time-Step Error 2.63 %
Max. Stable Time-Step Benchmark Run Time 32.83 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 12115 Hz
CVODE Steps Per AP 763
CVODE Benchmark Run Time 34.11 HH
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