Primary visual area layer 5 aspiny 484742372 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Pvalb-IRES-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001494
Cell_485611914.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001494
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Fast Spikers (FS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -89.59 mV
Rheobase Current Interval (0.10506, 0.10712] nA
Threshold Current Interval (0.46875, 0.52734] nA
Bias Current (to -80.00 mV) 0.0216 nA
Testing Temperature 34.0 °C
Stability Interval [-2.8125, 15.0] nA
AP 1-2 Amplitude Drop -0.7058 mV
AP 1 Steady State Amplitude Change -0.4122 mV
AP 1 Amplitude 47.0945 mV
AP 1 Width at Half Height 0.3400 ms
AP 1 Width (Peak To Trough) 2.0100 ms
AP 1 Rate of Change Peak to Trough -34.5317 mV/ms
AP 1 AHP Depth 22.3142 mV
AP2 Amplitude 47.8003 mV
AP2 Width at Half Height 0.3500 ms
AP 2 Width (Peak to Trough) 2.0600 ms
AP 2 Rate of Change Peak to Trough -34.2667 mV/ms
AP 2 AHP Depth 22.7891 mV
AP 1-2 Amplitude Change Percent 1.4987 %
AP 1-2 Half Width Change Percent 2.9412 %
AP 1-2 Rate of Change Peak to Trough Percent Change -0.7675 %
AP 1-2 AHP Depth Percent Change 2.1279 %
Input Resistance 478.1777 MΩ
AP 1 Delay Mean 19.6900 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 35.9200 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 19.1650 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 5.8824 %
Steady State Accommodation Mean 5.8824 %
Accommodation Rate to Steady State 0.1014 %/ms
Accommodation at Steady State Mean -26.5767 %
Accommodation Rate Mean at Steady State 2.9851 ms
ISI CV 20.3739
ISI Median 21.7700 ms
ISI Burst Mean Change 36.1676 %
Spike Rate (Strong Stimulation) 101.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 5.7100 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 12.6000 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 7.2100 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2048.4700 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 5744.68 µm2
Number of Stems 6.0
Number of Bifurcations 15.0
Number of Branches 36.0
Overall Width 160.858 µm
Overall Height 276.887 µm
Overall Depth 69.09 µm
Average Diameter 0.406921 µm
Total Length 1867.09 µm
Total Surface 2798.54 µm2
Total Volume 1707.8 µm3
Max Euclidean Distance 223.419 µm
Max Path Distance 269.987 µm
Max Branch Order 4.0
Average Contraction 0.939358
Total Fragmentation 1506.0
Partition Asymmetry 0.555556
Average Rall's Ratio 1.94
Average Bifurcation Angle Local 70.967 °
Average Bifurcation Angle Remote 63.8149 °
Fractal Dimension 1.01766
Complexity Summary
State Equations 122
Optimal Time-Step 0.02342 ms
Relative Complexity 10.38 HH
Model Size
Sections 36
Compartments 94
State Equations 122
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02342 ms
Optimal Time-Step Error 1.85 %
Optimal Time-Step Benchmark Run Time 10.38 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 4.07 %
Max. Stable Time-Step Benchmark Run Time 7.60 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 5111 Hz
CVODE Steps Per AP 1020
CVODE Benchmark Run Time 24.48 HH
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