Primary visual area layer 2/3 aspiny 464188580 Cell

Model Type:
Cell
Neurolex IDs: Visual cortex primary layer 2
Visual cortex primary layer 3
Keywords: Mus musculus, Htr3a-Cre_NO152
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001493
Cell_472421285.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001493
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Rapidly Adapting (RA)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -91.64 mV
Rheobase Current Interval (0.22614, 0.22911] nA
Threshold Current Interval (0.70312, 0.76172] nA
Bias Current (to -80.00 mV) 0.0730 nA
Testing Temperature 34.0 °C
Stability Interval [-0.9375, 15.0] nA
AP 1-2 Amplitude Drop N/A mV
AP 1 Steady State Amplitude Change N/A mV
AP 1 Amplitude 66.8834 mV
AP 1 Width at Half Height 0.6100 ms
AP 1 Width (Peak To Trough) 30.1500 ms
AP 1 Rate of Change Peak to Trough -4.0480 mV/ms
AP 1 AHP Depth 55.1627 mV
AP2 Amplitude N/A mV
AP2 Width at Half Height N/A ms
AP 2 Width (Peak to Trough) N/A ms
AP 2 Rate of Change Peak to Trough N/A mV/ms
AP 2 AHP Depth N/A mV
AP 1-2 Amplitude Change Percent N/A %
AP 1-2 Half Width Change Percent N/A %
AP 1-2 Rate of Change Peak to Trough Percent Change N/A %
AP 1-2 AHP Depth Percent Change N/A %
Input Resistance 150.5761 MΩ
AP 1 Delay Mean 12.5800 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean N/A ms
AP 2 Delay SD N/A ms
Burst 1 ISI Mean N/A ms
Burst 1 ISI SD N/A ms
Initial Accommodation Mean -100.0000 %
Steady State Accommodation Mean -100.0000 %
Accommodation Rate to Steady State N/A %/ms
Accommodation at Steady State Mean N/A %
Accommodation Rate Mean at Steady State N/A ms
ISI CV N/A
ISI Median N/A ms
ISI Burst Mean Change N/A %
Spike Rate (Strong Stimulation) 0.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 3.3200 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) N/A ms
AP 2 Delay SD (Strong Stimulation) N/A ms
Burst 1 ISI Mean (Strong Stimulation) N/A ms
Burst 1 ISI SD (Strong Stimulation) N/A ms
Ramp First Spike Time 1999.1200 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 4932.42 µm2
Number of Stems 5.0
Number of Bifurcations 21.0
Number of Branches 47.0
Overall Width 104.539 µm
Overall Height 169.881 µm
Overall Depth 36.58 µm
Average Diameter 0.386986 µm
Total Length 1918.17 µm
Total Surface 2825.99 µm2
Total Volume 1506.92 µm3
Max Euclidean Distance 128.161 µm
Max Path Distance 195.184 µm
Max Branch Order 4.0
Average Contraction 0.735445
Total Fragmentation 1835.0
Partition Asymmetry 0.356009
Average Rall's Ratio 2.29667
Average Bifurcation Angle Local 66.705 °
Average Bifurcation Angle Remote 70.7516 °
Fractal Dimension 1.10802
Complexity Summary
State Equations 113
Optimal Time-Step 0.00772 ms
Relative Complexity 17.89 HH
Model Size
Sections 47
Compartments 97
State Equations 113
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00772 ms
Optimal Time-Step Error 0.01 %
Optimal Time-Step Benchmark Run Time 17.89 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 0.04 %
Max. Stable Time-Step Benchmark Run Time 34.53 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 11164 Hz
CVODE Steps Per AP 15735
CVODE Benchmark Run Time 153.06 HH
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