Primary visual area layer 5 spiny 475744706 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Htr3a-Cre_NO152
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001492
Cell_478045347.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001492
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Regular Spikers (RS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -77.51 mV
Rheobase Current Interval (0.02380, 0.02563] nA
Threshold Current Interval (0.41016, 0.46875] nA
Bias Current (to -70.00 mV) 0.0118 nA
Testing Temperature 34.0 °C
Stability Interval [-2.5, 15.0] nA
AP 1-2 Amplitude Drop 3.2238 mV
AP 1 Steady State Amplitude Change 2.9143 mV
AP 1 Amplitude 40.8016 mV
AP 1 Width at Half Height 0.8300 ms
AP 1 Width (Peak To Trough) 4.2800 ms
AP 1 Rate of Change Peak to Trough -11.8953 mV/ms
AP 1 AHP Depth 10.1102 mV
AP2 Amplitude 37.5778 mV
AP2 Width at Half Height 0.8700 ms
AP 2 Width (Peak to Trough) 4.8100 ms
AP 2 Rate of Change Peak to Trough -9.8190 mV/ms
AP 2 AHP Depth 9.6513 mV
AP 1-2 Amplitude Change Percent -7.9011 %
AP 1-2 Half Width Change Percent 4.8193 %
AP 1-2 Rate of Change Peak to Trough Percent Change -17.4550 %
AP 1-2 AHP Depth Percent Change -4.5384 %
Input Resistance 551.3244 MΩ
AP 1 Delay Mean 112.3300 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 132.4600 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 20.2400 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -42.8571 %
Steady State Accommodation Mean -28.5714 %
Accommodation Rate to Steady State -0.0780 %/ms
Accommodation at Steady State Mean -92.3194 %
Accommodation Rate Mean at Steady State 128.0601 ms
ISI CV 2.9311
ISI Median 92.5400 ms
ISI Burst Mean Change 1.0929 %
Spike Rate (Strong Stimulation) 20.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 36.3400 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 49.2800 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 13.3850 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2132.8900 ms
Frequency Filter Type High-Pass
Frequency Filter Pass Above 36.5862 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 3628.48 µm2
Number of Stems 8.0
Number of Bifurcations 14.0
Number of Branches 36.0
Overall Width 243.226 µm
Overall Height 660.262 µm
Overall Depth 107.72 µm
Average Diameter 0.564819 µm
Total Length 2814.75 µm
Total Surface 5311.54 µm2
Total Volume 1739.45 µm3
Max Euclidean Distance 652.797 µm
Max Path Distance 695.792 µm
Max Branch Order 5.0
Average Contraction 0.908929
Total Fragmentation 2172.0
Partition Asymmetry 0.5
Average Rall's Ratio 2.79812
Average Bifurcation Angle Local 67.3771 °
Average Bifurcation Angle Remote 84.1829 °
Fractal Dimension 1.02311
Complexity Summary
State Equations 152
Optimal Time-Step 0.01064 ms
Relative Complexity 15.81 HH
Model Size
Sections 36
Compartments 136
State Equations 152
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.01064 ms
Optimal Time-Step Error 0.53 %
Optimal Time-Step Benchmark Run Time 15.81 HH
 
Maximum Stable Time-Step 0.125 ms
Maximum Stable Time-Step Error 2.24 %
Max. Stable Time-Step Benchmark Run Time 21.01 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 11715 Hz
CVODE Steps Per AP 720
CVODE Benchmark Run Time 20.91 HH
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