Primary visual area layer 2/3 sparsely spiny 324266189 Cell

Model Type:
Cell
Neurolex IDs: Visual cortex primary layer 2
Visual cortex primary layer 3
Keywords: Mus musculus, Sst-IRES-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001489
Cell_480629276.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001489
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Regular Spikers (RS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -84.04 mV
Rheobase Current Interval (0.08652, 0.08858] nA
Threshold Current Interval (0.46875, 0.52734] nA
Bias Current (to -70.00 mV) 0.0790 nA
Testing Temperature 34.0 °C
Stability Interval [-4.375, 15.0] nA
AP 1-2 Amplitude Drop 0.4024 mV
AP 1 Steady State Amplitude Change 1.8021 mV
AP 1 Amplitude 67.1465 mV
AP 1 Width at Half Height 0.4300 ms
AP 1 Width (Peak To Trough) 2.9600 ms
AP 1 Rate of Change Peak to Trough -27.6312 mV/ms
AP 1 AHP Depth 14.6419 mV
AP2 Amplitude 66.7441 mV
AP2 Width at Half Height 0.4300 ms
AP 2 Width (Peak to Trough) 3.3100 ms
AP 2 Rate of Change Peak to Trough -24.7633 mV/ms
AP 2 AHP Depth 15.2226 mV
AP 1-2 Amplitude Change Percent -0.5993 %
AP 1-2 Half Width Change Percent 0.0000 %
AP 1-2 Rate of Change Peak to Trough Percent Change -10.3791 %
AP 1-2 AHP Depth Percent Change 3.9657 %
Input Resistance 167.5920 MΩ
AP 1 Delay Mean 22.9100 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 45.2700 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 25.5300 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -38.4615 %
Steady State Accommodation Mean -38.4615 %
Accommodation Rate to Steady State -0.0414 %/ms
Accommodation at Steady State Mean -57.2857 %
Accommodation Rate Mean at Steady State 575.8472 ms
ISI CV 4.7645
ISI Median 49.3250 ms
ISI Burst Mean Change 28.3542 %
Spike Rate (Strong Stimulation) 45.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 7.4100 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 14.6700 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 7.9350 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2060.5400 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 5377.08 µm2
Number of Stems 5.0
Number of Bifurcations 12.0
Number of Branches 29.0
Overall Width 212.885 µm
Overall Height 266.796 µm
Overall Depth 80.6 µm
Average Diameter 0.394098 µm
Total Length 1777.51 µm
Total Surface 2614.7 µm2
Total Volume 1586.4 µm3
Max Euclidean Distance 188.747 µm
Max Path Distance 237.243 µm
Max Branch Order 5.0
Average Contraction 0.894447
Total Fragmentation 1495.0
Partition Asymmetry 0.383333
Average Rall's Ratio 1.79
Average Bifurcation Angle Local 69.3319 °
Average Bifurcation Angle Remote 63.5193 °
Fractal Dimension 1.03471
Complexity Summary
State Equations 115
Optimal Time-Step 0.02332 ms
Relative Complexity 10.49 HH
Model Size
Sections 29
Compartments 87
State Equations 115
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02332 ms
Optimal Time-Step Error 1.38 %
Optimal Time-Step Benchmark Run Time 10.49 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 3.48 %
Max. Stable Time-Step Benchmark Run Time 7.64 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 4918 Hz
CVODE Steps Per AP 1646
CVODE Benchmark Run Time 34.39 HH
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