Primary visual area layer 4 spiny 324025371 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Rorb-IRES2-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001488
Cell_472434498.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001488
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Fast Spikers (FS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -85.41 mV
Rheobase Current Interval (0.09933, 0.10254] nA
Threshold Current Interval (0.76172, 0.82031] nA
Bias Current (to -80.00 mV) 0.0307 nA
Testing Temperature 34.0 °C
Stability Interval [-3.4375, 15.0] nA
AP 1-2 Amplitude Drop 2.7295 mV
AP 1 Steady State Amplitude Change 3.6471 mV
AP 1 Amplitude 69.4195 mV
AP 1 Width at Half Height 0.9200 ms
AP 1 Width (Peak To Trough) 10.4200 ms
AP 1 Rate of Change Peak to Trough -8.1497 mV/ms
AP 1 AHP Depth 15.5003 mV
AP2 Amplitude 66.6900 mV
AP2 Width at Half Height 0.9300 ms
AP 2 Width (Peak to Trough) 10.6400 ms
AP 2 Rate of Change Peak to Trough -7.9327 mV/ms
AP 2 AHP Depth 17.7140 mV
AP 1-2 Amplitude Change Percent -3.9320 %
AP 1-2 Half Width Change Percent 1.0870 %
AP 1-2 Rate of Change Peak to Trough Percent Change -2.6625 %
AP 1-2 AHP Depth Percent Change 14.2818 %
Input Resistance 154.1350 MΩ
AP 1 Delay Mean 31.0100 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 74.9500 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 46.0300 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 12.5000 %
Steady State Accommodation Mean 0.0000 %
Accommodation Rate to Steady State 0.0000 %/ms
Accommodation at Steady State Mean -4.8023 %
Accommodation Rate Mean at Steady State 1.0328 ms
ISI CV 63.2416
ISI Median 45.9600 ms
ISI Burst Mean Change 9.5130 %
Spike Rate (Strong Stimulation) 68.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 10.1900 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 22.3900 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 13.3050 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2073.7600 ms
Frequency Filter Type Band-Pass
Frequency Filter Pass Above 34.5056 Hz
Frequency Filter Pass Below 138.6500 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 9184.74 µm2
Number of Stems 6.0
Number of Bifurcations 29.0
Number of Branches 64.0
Overall Width 400.233 µm
Overall Height 192.826 µm
Overall Depth 84.12 µm
Average Diameter 0.419376 µm
Total Length 3043.67 µm
Total Surface 4531.16 µm2
Total Volume 2742.91 µm3
Max Euclidean Distance 358.845 µm
Max Path Distance 429.623 µm
Max Branch Order 7.0
Average Contraction 0.806852
Total Fragmentation 2276.0
Partition Asymmetry 0.517625
Average Rall's Ratio 2.3845
Average Bifurcation Angle Local 79.7751 °
Average Bifurcation Angle Remote 61.5937 °
Fractal Dimension 1.07055
Complexity Summary
State Equations 177
Optimal Time-Step 0.01134 ms
Relative Complexity 18.37 HH
Model Size
Sections 63
Compartments 161
State Equations 177
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.01134 ms
Optimal Time-Step Error 0.07 %
Optimal Time-Step Benchmark Run Time 18.37 HH
 
Maximum Stable Time-Step 0.125 ms
Maximum Stable Time-Step Error 3.21 %
Max. Stable Time-Step Benchmark Run Time 26.04 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 12777 Hz
CVODE Steps Per AP 949
CVODE Benchmark Run Time 30.51 HH
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