Primary visual area layer 4 spiny 348592897 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Scnn1a-Tg2-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001481
Cell_472912107.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001481
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Accommodating Wide AP Multi-Spikers (awMS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -81.82 mV
Rheobase Current Interval (0.16479, 0.16685] nA
Threshold Current Interval (0.46875, 0.52734] nA
Bias Current (to -70.00 mV) 0.1253 nA
Testing Temperature 34.0 °C
Stability Interval [-3.125, 15.0] nA
AP 1-2 Amplitude Drop 7.3417 mV
AP 1 Steady State Amplitude Change N/A mV
AP 1 Amplitude 62.9589 mV
AP 1 Width at Half Height 0.6600 ms
AP 1 Width (Peak To Trough) 3.6000 ms
AP 1 Rate of Change Peak to Trough -20.0291 mV/ms
AP 1 AHP Depth 9.1459 mV
AP2 Amplitude 55.6172 mV
AP2 Width at Half Height 0.7400 ms
AP 2 Width (Peak to Trough) 2.5000 ms
AP 2 Rate of Change Peak to Trough -21.1329 mV/ms
AP 2 AHP Depth -2.7849 mV
AP 1-2 Amplitude Change Percent -11.6611 %
AP 1-2 Half Width Change Percent 12.1212 %
AP 1-2 Rate of Change Peak to Trough Percent Change 5.5111 %
AP 1-2 AHP Depth Percent Change -130.4495 %
Input Resistance 61.3407 MΩ
AP 1 Delay Mean 15.5100 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 23.4500 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean N/A ms
Burst 1 ISI SD N/A ms
Initial Accommodation Mean -100.0000 %
Steady State Accommodation Mean -100.0000 %
Accommodation Rate to Steady State N/A %/ms
Accommodation at Steady State Mean N/A %
Accommodation Rate Mean at Steady State N/A ms
ISI CV N/A
ISI Median 7.9400 ms
ISI Burst Mean Change N/A %
Spike Rate (Strong Stimulation) 1.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 2.3200 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 8.9100 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 5.8150 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2053.4800 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 10207.1 µm2
Number of Stems 10.0
Number of Bifurcations 40.0
Number of Branches 90.0
Overall Width 190.148 µm
Overall Height 547.531 µm
Overall Depth 87.16 µm
Average Diameter 0.433697 µm
Total Length 5757.46 µm
Total Surface 8417.44 µm2
Total Volume 3479.28 µm3
Max Euclidean Distance 459.605 µm
Max Path Distance 530.685 µm
Max Branch Order 10.0
Average Contraction 0.788418
Total Fragmentation 4619.0
Partition Asymmetry 0.527121
Average Rall's Ratio 2.09385
Average Bifurcation Angle Local 85.4201 °
Average Bifurcation Angle Remote 67.2915 °
Fractal Dimension 1.07792
Complexity Summary
State Equations 314
Optimal Time-Step 0.01029 ms
Relative Complexity 29.59 HH
Model Size
Sections 90
Compartments 298
State Equations 314
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.01029 ms
Optimal Time-Step Error 0.40 %
Optimal Time-Step Benchmark Run Time 29.59 HH
 
Maximum Stable Time-Step 0.125 ms
Maximum Stable Time-Step Error 8.50 %
Max. Stable Time-Step Benchmark Run Time 38.04 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 12105 Hz
CVODE Steps Per AP -650
CVODE Benchmark Run Time 11.20 HH
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