Primary visual area layer 4 spiny 395830185 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Scnn1a-Tg3-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001479
Cell_472363762.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001479
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Non-accommodating Regular Spikers (naRS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -92.10 mV
Rheobase Current Interval (0.07141, 0.07439] nA
Threshold Current Interval (0.70312, 0.76172] nA
Bias Current (to -80.00 mV) 0.0301 nA
Testing Temperature 34.0 °C
Stability Interval [-2.1875, 15.0] nA
AP 1-2 Amplitude Drop 3.0350 mV
AP 1 Steady State Amplitude Change 3.1538 mV
AP 1 Amplitude 78.7915 mV
AP 1 Width at Half Height 0.7500 ms
AP 1 Width (Peak To Trough) 13.2900 ms
AP 1 Rate of Change Peak to Trough -7.2941 mV/ms
AP 1 AHP Depth 18.1477 mV
AP2 Amplitude 75.7564 mV
AP2 Width at Half Height 0.7600 ms
AP 2 Width (Peak to Trough) 13.8300 ms
AP 2 Rate of Change Peak to Trough -6.7406 mV/ms
AP 2 AHP Depth 17.4666 mV
AP 1-2 Amplitude Change Percent -3.8520 %
AP 1-2 Half Width Change Percent 1.3333 %
AP 1-2 Rate of Change Peak to Trough Percent Change -7.5884 %
AP 1-2 AHP Depth Percent Change -3.7533 %
Input Resistance 385.9274 MΩ
AP 1 Delay Mean 62.9200 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 182.8700 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 114.9550 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean 0.0000 %
Accommodation Rate to Steady State 0.0000 %/ms
Accommodation at Steady State Mean -0.0000 %
Accommodation Rate Mean at Steady State 82106.7642 ms
ISI CV 15.6938
ISI Median 95.8100 ms
ISI Burst Mean Change -8.3285 %
Spike Rate (Strong Stimulation) 49.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 19.7500 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 42.9800 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 22.9700 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2064.0600 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 4052.5 µm2
Number of Stems 9.0
Number of Bifurcations 57.0
Number of Branches 123.0
Overall Width 155.6 µm
Overall Height 399.678 µm
Overall Depth 91.95 µm
Average Diameter 0.463884 µm
Total Length 4710.43 µm
Total Surface 7162.15 µm2
Total Volume 1905.23 µm3
Max Euclidean Distance 371.443 µm
Max Path Distance 508.633 µm
Max Branch Order 9.0
Average Contraction 0.766748
Total Fragmentation 3688.0
Partition Asymmetry 0.489084
Average Rall's Ratio 3.04933
Average Bifurcation Angle Local 77.1413 °
Average Bifurcation Angle Remote 81.3278 °
Fractal Dimension 1.10423
Complexity Summary
State Equations 280
Optimal Time-Step 0.00757 ms
Relative Complexity 41.02 HH
Model Size
Sections 122
Compartments 264
State Equations 280
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00757 ms
Optimal Time-Step Error 0.02 %
Optimal Time-Step Benchmark Run Time 41.02 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 0.28 %
Max. Stable Time-Step Benchmark Run Time 77.58 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 13129 Hz
CVODE Steps Per AP 995
CVODE Benchmark Run Time 47.09 HH
Website & Images Copyright NeuroML © 2019 For questions: Contact us Links: Search Test |  ModelDB WS