Primary visual area layer 4 spiny 314642645 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Rorb-IRES2-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001478
Cell_472299294.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001478
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Non-accommodating Regular Spikers (naRS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -88.37 mV
Rheobase Current Interval (0.05974, 0.06180] nA
Threshold Current Interval (0.46875, 0.52734] nA
Bias Current (to -80.00 mV) 0.0309 nA
Testing Temperature 34.0 °C
Stability Interval [-1.875, 15.0] nA
AP 1-2 Amplitude Drop 4.0941 mV
AP 1 Steady State Amplitude Change 4.5173 mV
AP 1 Amplitude 78.6842 mV
AP 1 Width at Half Height 0.7400 ms
AP 1 Width (Peak To Trough) 16.9000 ms
AP 1 Rate of Change Peak to Trough -5.7704 mV/ms
AP 1 AHP Depth 18.8352 mV
AP2 Amplitude 74.5901 mV
AP2 Width at Half Height 0.7300 ms
AP 2 Width (Peak to Trough) 16.5200 ms
AP 2 Rate of Change Peak to Trough -5.6994 mV/ms
AP 2 AHP Depth 19.5644 mV
AP 1-2 Amplitude Change Percent -5.2032 %
AP 1-2 Half Width Change Percent -1.3514 %
AP 1-2 Rate of Change Peak to Trough Percent Change -1.2295 %
AP 1-2 AHP Depth Percent Change 3.8718 %
Input Resistance 226.6658 MΩ
AP 1 Delay Mean 40.5900 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 158.6900 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 118.3950 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean -25.0000 %
Accommodation Rate to Steady State -0.1575 %/ms
Accommodation at Steady State Mean -99.3805 %
Accommodation Rate Mean at Steady State 14988334.0855 ms
ISI CV 46.3658
ISI Median 114.9000 ms
ISI Burst Mean Change 0.4996 %
Spike Rate (Strong Stimulation) 65.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 12.5800 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 25.4600 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 15.2250 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2078.4800 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 5638.98 µm2
Number of Stems 8.0
Number of Bifurcations 23.0
Number of Branches 54.0
Overall Width 218.446 µm
Overall Height 475.135 µm
Overall Depth 65.88 µm
Average Diameter 0.548647 µm
Total Length 2418.9 µm
Total Surface 4715.04 µm2
Total Volume 2096.51 µm3
Max Euclidean Distance 415.908 µm
Max Path Distance 518.411 µm
Max Branch Order 9.0
Average Contraction 0.850939
Total Fragmentation 2034.0
Partition Asymmetry 0.594203
Average Rall's Ratio 2.48
Average Bifurcation Angle Local 73.866 °
Average Bifurcation Angle Remote 80.4047 °
Fractal Dimension 1.05907
Complexity Summary
State Equations 145
Optimal Time-Step 0.00758 ms
Relative Complexity 21.63 HH
Model Size
Sections 53
Compartments 129
State Equations 145
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00758 ms
Optimal Time-Step Error 0.02 %
Optimal Time-Step Benchmark Run Time 21.63 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 0.38 %
Max. Stable Time-Step Benchmark Run Time 40.98 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 14582 Hz
CVODE Steps Per AP 852
CVODE Benchmark Run Time 24.91 HH
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