Primary visual area layer 5 aspiny 469801569 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Pvalb-IRES-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001476
Cell_473465774.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001476
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Fast Spikers (FS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -92.09 mV
Rheobase Current Interval (0.38132, 0.38452] nA
Threshold Current Interval (0.76172, 0.82031] nA
Bias Current (to -80.00 mV) 0.0346 nA
Testing Temperature 34.0 °C
Stability Interval [-4.0625, 15.0] nA
AP 1-2 Amplitude Drop 3.8755 mV
AP 1 Steady State Amplitude Change 6.8245 mV
AP 1 Amplitude 56.5128 mV
AP 1 Width at Half Height 0.3100 ms
AP 1 Width (Peak To Trough) 1.3200 ms
AP 1 Rate of Change Peak to Trough -59.6553 mV/ms
AP 1 AHP Depth 22.2322 mV
AP2 Amplitude 52.6372 mV
AP2 Width at Half Height 0.3300 ms
AP 2 Width (Peak to Trough) 1.3900 ms
AP 2 Rate of Change Peak to Trough -54.2424 mV/ms
AP 2 AHP Depth 22.7598 mV
AP 1-2 Amplitude Change Percent -6.8578 %
AP 1-2 Half Width Change Percent 6.4516 %
AP 1-2 Rate of Change Peak to Trough Percent Change -9.0735 %
AP 1-2 AHP Depth Percent Change 2.3728 %
Input Resistance 404.7644 MΩ
AP 1 Delay Mean 4.3100 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 11.1900 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 7.4500 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean 2.7027 %
Accommodation Rate to Steady State 0.0702 %/ms
Accommodation at Steady State Mean -37.7519 %
Accommodation Rate Mean at Steady State 14.6244 ms
ISI CV 27.1661
ISI Median 10.6300 ms
ISI Burst Mean Change 16.5698 %
Spike Rate (Strong Stimulation) 190.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 5.2200 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 9.3200 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 4.1350 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 1444.5500 ms
Frequency Filter Type High-Pass
Frequency Filter Pass Above 128.2265 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 24179.5 µm2
Number of Stems 8.0
Number of Bifurcations 28.0
Number of Branches 64.0
Overall Width 283.618 µm
Overall Height 347.3 µm
Overall Depth 80.8 µm
Average Diameter 0.501588 µm
Total Length 4404.48 µm
Total Surface 7972.69 µm2
Total Volume 6985.8 µm3
Max Euclidean Distance 273.837 µm
Max Path Distance 412.966 µm
Max Branch Order 6.0
Average Contraction 0.774326
Total Fragmentation 3421.0
Partition Asymmetry 0.522727
Average Rall's Ratio 2.53156
Average Bifurcation Angle Local 77.8542 °
Average Bifurcation Angle Remote 68.9444 °
Fractal Dimension 1.08976
Complexity Summary
State Equations 250
Optimal Time-Step 0.02402 ms
Relative Complexity 14.87 HH
Model Size
Sections 64
Compartments 222
State Equations 250
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02402 ms
Optimal Time-Step Error 2.91 %
Optimal Time-Step Benchmark Run Time 14.87 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 5.55 %
Max. Stable Time-Step Benchmark Run Time 11.16 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 4218 Hz
CVODE Steps Per AP 57862
CVODE Benchmark Run Time 1368.62 HH
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