Primary visual area layer 5 spiny 485880739 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Rbp4-Cre_KL100
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001475
Cell_486509010.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001475
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Accommodating Wide AP Multi-Spikers (awMS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -85.63 mV
Rheobase Current Interval (0.08789, 0.09155] nA
Threshold Current Interval (0.87891, 0.93750] nA
Bias Current (to -80.00 mV) 0.0363 nA
Testing Temperature 34.0 °C
Stability Interval [-7.8125, 15.0] nA
AP 1-2 Amplitude Drop 4.4560 mV
AP 1 Steady State Amplitude Change 2.4115 mV
AP 1 Amplitude 84.3830 mV
AP 1 Width at Half Height 0.6500 ms
AP 1 Width (Peak To Trough) 8.8800 ms
AP 1 Rate of Change Peak to Trough -9.8690 mV/ms
AP 1 AHP Depth 3.2537 mV
AP2 Amplitude 79.9270 mV
AP2 Width at Half Height 0.6000 ms
AP 2 Width (Peak to Trough) 17.7200 ms
AP 2 Rate of Change Peak to Trough -5.6887 mV/ms
AP 2 AHP Depth 20.8767 mV
AP 1-2 Amplitude Change Percent -5.2807 %
AP 1-2 Half Width Change Percent -7.6923 %
AP 1-2 Rate of Change Peak to Trough Percent Change -42.3579 %
AP 1-2 AHP Depth Percent Change 541.6336 %
Input Resistance 153.6564 MΩ
AP 1 Delay Mean 68.7100 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 80.7900 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 55.3300 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -25.0000 %
Steady State Accommodation Mean -25.0000 %
Accommodation Rate to Steady State -0.0527 %/ms
Accommodation at Steady State Mean -92.3586 %
Accommodation Rate Mean at Steady State 103.4326 ms
ISI CV 1.7325
ISI Median 164.9850 ms
ISI Burst Mean Change 716.0596 %
Spike Rate (Strong Stimulation) 3.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 17.6800 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 23.0700 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 5.4300 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2137.0800 ms
Frequency Filter Type High-Pass
Frequency Filter Pass Above 66.6535 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 14115.0 µm2
Number of Stems 8.0
Number of Bifurcations 43.0
Number of Branches 94.0
Overall Width 277.108 µm
Overall Height 679.614 µm
Overall Depth 97.65 µm
Average Diameter 0.58247 µm
Total Length 5133.74 µm
Total Surface 10076.4 µm2
Total Volume 5345.05 µm3
Max Euclidean Distance 597.674 µm
Max Path Distance 756.766 µm
Max Branch Order 16.0
Average Contraction 0.915884
Total Fragmentation 4208.0
Partition Asymmetry 0.466017
Average Rall's Ratio 1.89167
Average Bifurcation Angle Local 72.0567 °
Average Bifurcation Angle Remote 68.7436 °
Fractal Dimension 1.02235
Complexity Summary
State Equations 280
Optimal Time-Step 0.02058 ms
Relative Complexity 19.45 HH
Model Size
Sections 94
Compartments 252
State Equations 280
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02058 ms
Optimal Time-Step Error 0.24 %
Optimal Time-Step Benchmark Run Time 19.45 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 21.29 %
Max. Stable Time-Step Benchmark Run Time 12.51 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 4309 Hz
CVODE Steps Per AP 1241
CVODE Benchmark Run Time 44.02 HH
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