Primary visual area layer 6a spiny 325941643 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 6a
Keywords: Mus musculus, Rbp4-Cre_KL100
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001470
Cell_473871592.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001470
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Fast Spikers (FS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -85.14 mV
Rheobase Current Interval (0.16273, 0.16479] nA
Threshold Current Interval (0.46875, 0.52734] nA
Bias Current (to -80.00 mV) 0.0437 nA
Testing Temperature 34.0 °C
Stability Interval [-2.1875, 15.0] nA
AP 1-2 Amplitude Drop 8.1831 mV
AP 1 Steady State Amplitude Change 10.3732 mV
AP 1 Amplitude 78.4397 mV
AP 1 Width at Half Height 0.8900 ms
AP 1 Width (Peak To Trough) 9.0800 ms
AP 1 Rate of Change Peak to Trough -10.7046 mV/ms
AP 1 AHP Depth 18.7582 mV
AP2 Amplitude 70.2566 mV
AP2 Width at Half Height 0.8800 ms
AP 2 Width (Peak to Trough) 8.7400 ms
AP 2 Rate of Change Peak to Trough -10.4393 mV/ms
AP 2 AHP Depth 20.9825 mV
AP 1-2 Amplitude Change Percent -10.4323 %
AP 1-2 Half Width Change Percent -1.1236 %
AP 1-2 Rate of Change Peak to Trough Percent Change -2.4788 %
AP 1-2 AHP Depth Percent Change 11.8583 %
Input Resistance 115.0975 MΩ
AP 1 Delay Mean 12.2600 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 44.5600 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 31.8250 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean -7.6923 %
Accommodation Rate to Steady State -0.1726 %/ms
Accommodation at Steady State Mean -0.0000 %
Accommodation Rate Mean at Steady State 4.1318 ms
ISI CV 71.7409
ISI Median 30.9800 ms
ISI Burst Mean Change -2.9412 %
Spike Rate (Strong Stimulation) 36.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 2.9000 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 18.2300 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 14.9800 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2021.9100 ms
Frequency Filter Type Band-Pass
Frequency Filter Pass Above 49.3263 Hz
Frequency Filter Pass Below 96.9059 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 7141.16 µm2
Number of Stems 13.0
Number of Bifurcations 31.0
Number of Branches 75.0
Overall Width 261.205 µm
Overall Height 532.038 µm
Overall Depth 104.2 µm
Average Diameter 0.482533 µm
Total Length 5069.85 µm
Total Surface 8022.67 µm2
Total Volume 2772.25 µm3
Max Euclidean Distance 447.802 µm
Max Path Distance 689.701 µm
Max Branch Order 11.0
Average Contraction 0.788073
Total Fragmentation 3747.0
Partition Asymmetry 0.450368
Average Rall's Ratio 2.59933
Average Bifurcation Angle Local 72.9948 °
Average Bifurcation Angle Remote 66.8378 °
Fractal Dimension 1.07283
Complexity Summary
State Equations 267
Optimal Time-Step 0.00766 ms
Relative Complexity 36.78 HH
Model Size
Sections 75
Compartments 251
State Equations 267
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00766 ms
Optimal Time-Step Error 0.13 %
Optimal Time-Step Benchmark Run Time 36.78 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 0.72 %
Max. Stable Time-Step Benchmark Run Time 70.45 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 12054 Hz
CVODE Steps Per AP 694
CVODE Benchmark Run Time 35.20 HH
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