Primary visual area layer 5 spiny 485909730 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Cux2-CreERT2
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001468
Cell_486509232.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001468
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Accommodating Wide AP Multi-Spikers (awMS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -91.20 mV
Rheobase Current Interval (0.08034, 0.08240] nA
Threshold Current Interval (0.46875, 0.52734] nA
Bias Current (to -80.00 mV) 0.0356 nA
Testing Temperature 34.0 °C
Stability Interval [-1.5625, 15.0] nA
AP 1-2 Amplitude Drop 7.2737 mV
AP 1 Steady State Amplitude Change 9.4103 mV
AP 1 Amplitude 55.1369 mV
AP 1 Width at Half Height 0.6900 ms
AP 1 Width (Peak To Trough) 6.9500 ms
AP 1 Rate of Change Peak to Trough -9.4577 mV/ms
AP 1 AHP Depth 10.5942 mV
AP2 Amplitude 47.8632 mV
AP2 Width at Half Height 0.7700 ms
AP 2 Width (Peak to Trough) 11.8200 ms
AP 2 Rate of Change Peak to Trough -5.3217 mV/ms
AP 2 AHP Depth 15.0394 mV
AP 1-2 Amplitude Change Percent -13.1921 %
AP 1-2 Half Width Change Percent 11.5942 %
AP 1-2 Rate of Change Peak to Trough Percent Change -43.7315 %
AP 1-2 AHP Depth Percent Change 41.9596 %
Input Resistance 293.4839 MΩ
AP 1 Delay Mean 28.2700 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 44.7100 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 21.3050 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -41.6667 %
Steady State Accommodation Mean -41.6667 %
Accommodation Rate to Steady State -0.0795 %/ms
Accommodation at Steady State Mean -72.4422 %
Accommodation Rate Mean at Steady State 269.7062 ms
ISI CV 3.9587
ISI Median 56.7200 ms
ISI Burst Mean Change 59.1849 %
Spike Rate (Strong Stimulation) 2.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 8.0500 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 16.9200 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 9.0450 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2062.7500 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 2888.58 µm2
Number of Stems 8.0
Number of Bifurcations 19.0
Number of Branches 46.0
Overall Width 175.563 µm
Overall Height 544.811 µm
Overall Depth 56.72 µm
Average Diameter 0.44357 µm
Total Length 2400.41 µm
Total Surface 3595.87 µm2
Total Volume 1149.45 µm3
Max Euclidean Distance 445.769 µm
Max Path Distance 513.032 µm
Max Branch Order 6.0
Average Contraction 0.91955
Total Fragmentation 1918.0
Partition Asymmetry 0.460526
Average Rall's Ratio 2.44625
Average Bifurcation Angle Local 65.8814 °
Average Bifurcation Angle Remote 78.1883 °
Fractal Dimension 1.01946
Complexity Summary
State Equations 136
Optimal Time-Step 0.00755 ms
Relative Complexity 19.66 HH
Model Size
Sections 46
Compartments 120
State Equations 136
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00755 ms
Optimal Time-Step Error 0.63 %
Optimal Time-Step Benchmark Run Time 19.66 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 2.22 %
Max. Stable Time-Step Benchmark Run Time 37.08 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 11787 Hz
CVODE Steps Per AP 944
CVODE Benchmark Run Time 20.71 HH
Website & Images Copyright NeuroML © 2019 For questions: Contact us Links: Search Test |  ModelDB WS