Primary visual area layer 5 spiny 484559000 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Rorb-IRES2-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001467
Cell_485591806.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001467
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Accommodating Wide AP Multi-Spikers (awMS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -86.21 mV
Rheobase Current Interval (0.17395, 0.17830] nA
Threshold Current Interval (1.05469, 1.11328] nA
Bias Current (to -80.00 mV) 0.0708 nA
Testing Temperature 34.0 °C
Stability Interval [-8.4375, 15.0] nA
AP 1-2 Amplitude Drop 2.1119 mV
AP 1 Steady State Amplitude Change 0.3397 mV
AP 1 Amplitude 69.9851 mV
AP 1 Width at Half Height 0.6000 ms
AP 1 Width (Peak To Trough) 7.0100 ms
AP 1 Rate of Change Peak to Trough -10.9718 mV/ms
AP 1 AHP Depth 6.9270 mV
AP2 Amplitude 67.8732 mV
AP2 Width at Half Height 0.5800 ms
AP 2 Width (Peak to Trough) 16.7200 ms
AP 2 Rate of Change Peak to Trough -5.2458 mV/ms
AP 2 AHP Depth 19.8369 mV
AP 1-2 Amplitude Change Percent -3.0177 %
AP 1-2 Half Width Change Percent -3.3333 %
AP 1-2 Rate of Change Peak to Trough Percent Change -52.1880 %
AP 1-2 AHP Depth Percent Change 186.3722 %
Input Resistance 86.6249 MΩ
AP 1 Delay Mean 25.3200 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 37.8000 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 42.0750 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean 0.0000 %
Accommodation Rate to Steady State 0.0000 %/ms
Accommodation at Steady State Mean -74.7087 %
Accommodation Rate Mean at Steady State 0.8117 ms
ISI CV 6.6871
ISI Median 47.7400 ms
ISI Burst Mean Change 474.2788 %
Spike Rate (Strong Stimulation) 42.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 7.6100 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 12.9900 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 35.6400 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2065.6600 ms
Frequency Filter Type High-Pass
Frequency Filter Pass Above 40.9199 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 6260.46 µm2
Number of Stems 7.0
Number of Bifurcations 20.0
Number of Branches 47.0
Overall Width 200.864 µm
Overall Height 482.32 µm
Overall Depth 59.01 µm
Average Diameter 0.35871 µm
Total Length 2540.48 µm
Total Surface 3330.89 µm2
Total Volume 1865.87 µm3
Max Euclidean Distance 447.839 µm
Max Path Distance 519.617 µm
Max Branch Order 7.0
Average Contraction 0.907765
Total Fragmentation 2085.0
Partition Asymmetry 0.55
Average Rall's Ratio 2.50056
Average Bifurcation Angle Local 74.3606 °
Average Bifurcation Angle Remote 76.3158 °
Fractal Dimension 1.02359
Complexity Summary
State Equations 163
Optimal Time-Step 0.02575 ms
Relative Complexity 10.93 HH
Model Size
Sections 47
Compartments 135
State Equations 163
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02575 ms
Optimal Time-Step Error 2.34 %
Optimal Time-Step Benchmark Run Time 10.93 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 3.78 %
Max. Stable Time-Step Benchmark Run Time 8.79 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 4114 Hz
CVODE Steps Per AP 1636
CVODE Benchmark Run Time 37.88 HH
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