Primary visual area layer 5 spiny 483061182 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Cux2-CreERT2
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001466
Cell_485510685.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001466
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Non-accommodating Regular Spikers (naRS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -86.70 mV
Rheobase Current Interval (0.11169, 0.11261] nA
Threshold Current Interval (0.17578, 0.23438] nA
Bias Current (to -80.00 mV) 0.0249 nA
Testing Temperature 34.0 °C
Stability Interval [-0.625, 15.0] nA
AP 1-2 Amplitude Drop 1.8680 mV
AP 1 Steady State Amplitude Change 1.6751 mV
AP 1 Amplitude 68.5521 mV
AP 1 Width at Half Height 0.6500 ms
AP 1 Width (Peak To Trough) 33.5900 ms
AP 1 Rate of Change Peak to Trough -2.6111 mV/ms
AP 1 AHP Depth 19.1539 mV
AP2 Amplitude 66.6841 mV
AP2 Width at Half Height 0.7600 ms
AP 2 Width (Peak to Trough) 6.7200 ms
AP 2 Rate of Change Peak to Trough -13.0276 mV/ms
AP 2 AHP Depth 20.8615 mV
AP 1-2 Amplitude Change Percent -2.7249 %
AP 1-2 Half Width Change Percent 16.9231 %
AP 1-2 Rate of Change Peak to Trough Percent Change 398.9373 %
AP 1-2 AHP Depth Percent Change 8.9152 %
Input Resistance 254.0627 MΩ
AP 1 Delay Mean 9.2100 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 98.6400 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 84.2350 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 20.0000 %
Steady State Accommodation Mean 20.0000 %
Accommodation Rate to Steady State 0.2028 %/ms
Accommodation at Steady State Mean -0.0000 %
Accommodation Rate Mean at Steady State 8783.9219 ms
ISI CV 13.2776
ISI Median 67.4200 ms
ISI Burst Mean Change -11.6180 %
Spike Rate (Strong Stimulation) 31.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 1.3500 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 10.7300 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 9.4400 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2029.7800 ms
Frequency Filter Type Low-Pass
Frequency Filter Pass Below 102.8714 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 5293.73 µm2
Number of Stems 9.0
Number of Bifurcations 25.0
Number of Branches 59.0
Overall Width 167.279 µm
Overall Height 434.396 µm
Overall Depth 73.78 µm
Average Diameter 0.355652 µm
Total Length 2461.13 µm
Total Surface 3176.78 µm2
Total Volume 1615.67 µm3
Max Euclidean Distance 393.563 µm
Max Path Distance 432.199 µm
Max Branch Order 9.0
Average Contraction 0.916957
Total Fragmentation 1995.0
Partition Asymmetry 0.491619
Average Rall's Ratio 2.403
Average Bifurcation Angle Local 83.398 °
Average Bifurcation Angle Remote 70.7472 °
Fractal Dimension 1.02474
Complexity Summary
State Equations 145
Optimal Time-Step 0.00764 ms
Relative Complexity 20.63 HH
Model Size
Sections 59
Compartments 129
State Equations 145
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00764 ms
Optimal Time-Step Error 0.10 %
Optimal Time-Step Benchmark Run Time 20.63 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 1.03 %
Max. Stable Time-Step Benchmark Run Time 39.37 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 8871 Hz
CVODE Steps Per AP 525
CVODE Benchmark Run Time 14.63 HH
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