Primary visual area layer 5 aspiny 396968721 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Gad2-IRES-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001464
Cell_472447460.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001464
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Fast Spikers (FS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -86.07 mV
Rheobase Current Interval (0.05127, 0.05287] nA
Threshold Current Interval (0.35156, 0.41016] nA
Bias Current (to -80.00 mV) 0.0064 nA
Testing Temperature 34.0 °C
Stability Interval [-2.8125, 15.0] nA
AP 1-2 Amplitude Drop 1.9932 mV
AP 1 Steady State Amplitude Change 1.7459 mV
AP 1 Amplitude 56.1191 mV
AP 1 Width at Half Height 0.2800 ms
AP 1 Width (Peak To Trough) 1.8100 ms
AP 1 Rate of Change Peak to Trough -44.6292 mV/ms
AP 1 AHP Depth 24.6598 mV
AP2 Amplitude 54.1259 mV
AP2 Width at Half Height 0.2800 ms
AP 2 Width (Peak to Trough) 1.8400 ms
AP 2 Rate of Change Peak to Trough -43.3240 mV/ms
AP 2 AHP Depth 25.5902 mV
AP 1-2 Amplitude Change Percent -3.5517 %
AP 1-2 Half Width Change Percent 0.0000 %
AP 1-2 Rate of Change Peak to Trough Percent Change -2.9246 %
AP 1-2 AHP Depth Percent Change 3.7731 %
Input Resistance 814.1385 MΩ
AP 1 Delay Mean 30.4800 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 63.4700 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 35.6350 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 10.0000 %
Steady State Accommodation Mean 10.0000 %
Accommodation Rate to Steady State 0.0983 %/ms
Accommodation at Steady State Mean -10.0864 %
Accommodation Rate Mean at Steady State 0.0563 ms
ISI CV 42.6621
ISI Median 36.3900 ms
ISI Burst Mean Change 16.0352 %
Spike Rate (Strong Stimulation) 63.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 10.7200 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 21.8600 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 12.4400 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2406.6300 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 1349.04 µm2
Number of Stems 7.0
Number of Bifurcations 17.0
Number of Branches 41.0
Overall Width 183.098 µm
Overall Height 321.247 µm
Overall Depth 96.73 µm
Average Diameter 0.394184 µm
Total Length 2001.88 µm
Total Surface 2657.94 µm2
Total Volume 624.614 µm3
Max Euclidean Distance 257.099 µm
Max Path Distance 309.218 µm
Max Branch Order 5.0
Average Contraction 0.915254
Total Fragmentation 1580.0
Partition Asymmetry 0.5
Average Rall's Ratio 1.85167
Average Bifurcation Angle Local 77.2445 °
Average Bifurcation Angle Remote 61.8505 °
Fractal Dimension 1.02666
Complexity Summary
State Equations 133
Optimal Time-Step 0.02606 ms
Relative Complexity 9.96 HH
Model Size
Sections 41
Compartments 105
State Equations 133
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02606 ms
Optimal Time-Step Error 2.56 %
Optimal Time-Step Benchmark Run Time 9.96 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 3.45 %
Max. Stable Time-Step Benchmark Run Time 8.11 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 4710 Hz
CVODE Steps Per AP 1240
CVODE Benchmark Run Time 29.20 HH
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