Primary visual area layer 4 spiny 486146717 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Cux2-CreERT2
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001463
Cell_486557284.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001463
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Regular Spikers (RS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -92.98 mV
Rheobase Current Interval (0.10620, 0.10986] nA
Threshold Current Interval (0.87891, 0.93750] nA
Bias Current (to -80.00 mV) 0.0428 nA
Testing Temperature 34.0 °C
Stability Interval [-2.5, 15.0] nA
AP 1-2 Amplitude Drop 0.8146 mV
AP 1 Steady State Amplitude Change 5.6996 mV
AP 1 Amplitude 64.5704 mV
AP 1 Width at Half Height 0.7700 ms
AP 1 Width (Peak To Trough) 11.2300 ms
AP 1 Rate of Change Peak to Trough -7.0275 mV/ms
AP 1 AHP Depth 14.3489 mV
AP2 Amplitude 63.7558 mV
AP2 Width at Half Height 0.7900 ms
AP 2 Width (Peak to Trough) 12.2700 ms
AP 2 Rate of Change Peak to Trough -6.3519 mV/ms
AP 2 AHP Depth 14.1822 mV
AP 1-2 Amplitude Change Percent -1.2615 %
AP 1-2 Half Width Change Percent 2.5974 %
AP 1-2 Rate of Change Peak to Trough Percent Change -9.6140 %
AP 1-2 AHP Depth Percent Change -1.1620 %
Input Resistance 305.7161 MΩ
AP 1 Delay Mean 44.0000 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 77.8800 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 35.9300 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -50.0000 %
Steady State Accommodation Mean -33.3333 %
Accommodation Rate to Steady State -0.0732 %/ms
Accommodation at Steady State Mean -83.3041 %
Accommodation Rate Mean at Steady State 188.2135 ms
ISI CV 3.1466
ISI Median 121.3800 ms
ISI Burst Mean Change 12.1015 %
Spike Rate (Strong Stimulation) 50.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 13.7600 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 29.9000 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 16.8700 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2076.5200 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 3614.39 µm2
Number of Stems 9.0
Number of Bifurcations 36.0
Number of Branches 81.0
Overall Width 152.593 µm
Overall Height 524.433 µm
Overall Depth 58.71 µm
Average Diameter 0.552319 µm
Total Length 3595.91 µm
Total Surface 6503.06 µm2
Total Volume 1938.12 µm3
Max Euclidean Distance 437.207 µm
Max Path Distance 473.869 µm
Max Branch Order 8.0
Average Contraction 0.923975
Total Fragmentation 2917.0
Partition Asymmetry 0.492165
Average Rall's Ratio 1.994
Average Bifurcation Angle Local 67.7965 °
Average Bifurcation Angle Remote 62.4402 °
Fractal Dimension 1.02122
Complexity Summary
State Equations 199
Optimal Time-Step 0.00781 ms
Relative Complexity 28.64 HH
Model Size
Sections 81
Compartments 183
State Equations 199
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00781 ms
Optimal Time-Step Error 0.11 %
Optimal Time-Step Benchmark Run Time 28.64 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 0.81 %
Max. Stable Time-Step Benchmark Run Time 55.88 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 11355 Hz
CVODE Steps Per AP 857
CVODE Benchmark Run Time 29.29 HH
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