Primary visual area layer 4 spiny 386049446 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Nr5a1-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001462
Cell_472451419.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001462
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Regular Spikers (RS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -99.71 mV
Rheobase Current Interval (0.09819, 0.10117] nA
Threshold Current Interval (0.70312, 0.76172] nA
Bias Current (to -80.00 mV) 0.0656 nA
Testing Temperature 34.0 °C
Stability Interval [-1.5625, 15.0] nA
AP 1-2 Amplitude Drop 3.8198 mV
AP 1 Steady State Amplitude Change 7.8719 mV
AP 1 Amplitude 73.4823 mV
AP 1 Width at Half Height 0.6300 ms
AP 1 Width (Peak To Trough) 3.1300 ms
AP 1 Rate of Change Peak to Trough -30.5994 mV/ms
AP 1 AHP Depth 22.2937 mV
AP2 Amplitude 69.6625 mV
AP2 Width at Half Height 0.6500 ms
AP 2 Width (Peak to Trough) 3.3700 ms
AP 2 Rate of Change Peak to Trough -27.2173 mV/ms
AP 2 AHP Depth 22.0598 mV
AP 1-2 Amplitude Change Percent -5.1982 %
AP 1-2 Half Width Change Percent 3.1746 %
AP 1-2 Rate of Change Peak to Trough Percent Change -11.0527 %
AP 1-2 AHP Depth Percent Change -1.0491 %
Input Resistance 296.7924 MΩ
AP 1 Delay Mean 56.9900 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 101.3500 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 64.8150 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -20.0000 %
Steady State Accommodation Mean -20.0000 %
Accommodation Rate to Steady State -0.0711 %/ms
Accommodation at Steady State Mean -54.4248 %
Accommodation Rate Mean at Steady State 1.8181 ms
ISI CV 7.9487
ISI Median 97.9400 ms
ISI Burst Mean Change 92.2227 %
Spike Rate (Strong Stimulation) 80.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 14.7000 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 27.4700 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 12.8800 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2074.2100 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 3069.58 µm2
Number of Stems 6.0
Number of Bifurcations 18.0
Number of Branches 42.0
Overall Width 222.083 µm
Overall Height 429.023 µm
Overall Depth 61.97 µm
Average Diameter 0.469964 µm
Total Length 2368.15 µm
Total Surface 3755.17 µm2
Total Volume 1249.21 µm3
Max Euclidean Distance 346.106 µm
Max Path Distance 386.801 µm
Max Branch Order 6.0
Average Contraction 0.925868
Total Fragmentation 1955.0
Partition Asymmetry 0.458201
Average Rall's Ratio 2.14556
Average Bifurcation Angle Local 70.6036 °
Average Bifurcation Angle Remote 57.4211 °
Fractal Dimension 1.02172
Complexity Summary
State Equations 134
Optimal Time-Step 0.00783 ms
Relative Complexity 19.97 HH
Model Size
Sections 42
Compartments 118
State Equations 134
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00783 ms
Optimal Time-Step Error 0.25 %
Optimal Time-Step Benchmark Run Time 19.97 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 0.78 %
Max. Stable Time-Step Benchmark Run Time 39.08 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 13573 Hz
CVODE Steps Per AP 919
CVODE Benchmark Run Time 23.40 HH
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