posteromedial visual area layer 5 spiny 479770916 Cell

Model Type:
Cell
Neurolex IDs: Posteromedial visual area layer 4
Keywords: Mus musculus, Rorb-IRES2-Cre, pyramidal
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001461
Cell_482525264.cell.nml
( view NeuroML )
NMLCH000104
Ih.channel.nml
( view NeuroML )
NMLCH000114
pas.channel.nml
( view NeuroML )
NMLCH000129
Kd.channel.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001461
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Accommodating Wide AP Multi-Spikers (awMS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -81.93 mV
Rheobase Current Interval (0.18677, 0.19043] nA
Threshold Current Interval (0.87891, 0.93750] nA
Bias Current (to -70.00 mV) 0.1591 nA
Testing Temperature 34.0 °C
Stability Interval [-8.4375, 15.0] nA
AP 1-2 Amplitude Drop 4.1466 mV
AP 1 Steady State Amplitude Change 0.9355 mV
AP 1 Amplitude 70.8929 mV
AP 1 Width at Half Height 0.5600 ms
AP 1 Width (Peak To Trough) 11.7400 ms
AP 1 Rate of Change Peak to Trough -6.4532 mV/ms
AP 1 AHP Depth 4.8682 mV
AP2 Amplitude 66.7463 mV
AP2 Width at Half Height 0.5400 ms
AP 2 Width (Peak to Trough) 15.1700 ms
AP 2 Rate of Change Peak to Trough -5.5434 mV/ms
AP 2 AHP Depth 17.3476 mV
AP 1-2 Amplitude Change Percent -5.8491 %
AP 1-2 Half Width Change Percent -3.5714 %
AP 1-2 Rate of Change Peak to Trough Percent Change -14.0986 %
AP 1-2 AHP Depth Percent Change 256.3409 %
Input Resistance 67.6758 MΩ
AP 1 Delay Mean 21.1000 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 38.5100 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 32.7100 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean 0.0000 %
Steady State Accommodation Mean 0.0000 %
Accommodation Rate to Steady State 0.0000 %/ms
Accommodation at Steady State Mean -60.4312 %
Accommodation Rate Mean at Steady State 1.9912 ms
ISI CV 10.5846
ISI Median 43.5600 ms
ISI Burst Mean Change 175.7611 %
Spike Rate (Strong Stimulation) 0.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 5.9400 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) N/A ms
AP 2 Delay SD (Strong Stimulation) N/A ms
Burst 1 ISI Mean (Strong Stimulation) N/A ms
Burst 1 ISI SD (Strong Stimulation) N/A ms
Ramp First Spike Time 2054.1200 ms
Frequency Filter Type High-Pass
Frequency Filter Pass Above 119.6691 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 6513.02 µm2
Number of Stems 11.0
Number of Bifurcations 51.0
Number of Branches 113.0
Overall Width 293.198 µm
Overall Height 728.879 µm
Overall Depth 134.32 µm
Average Diameter 0.364527 µm
Total Length 6269.25 µm
Total Surface 7474.15 µm2
Total Volume 2430.03 µm3
Max Euclidean Distance 633.287 µm
Max Path Distance 792.357 µm
Max Branch Order 18.0
Average Contraction 0.927539
Total Fragmentation 4782.0
Partition Asymmetry 0.537911
Average Rall's Ratio 1.7575
Average Bifurcation Angle Local 76.463 °
Average Bifurcation Angle Remote 66.3135 °
Fractal Dimension 1.0182
Complexity Summary
Relative Complexity 63.33 HH
State Equations 333
Optimal Time-Step 0.02304 ms
Model Size
Sections 113
Compartments 305
State Equations 333
Variable Time-Step Complexity
CVODE Steady State Step Frequency 4474 Hz
CVODE Steps Per AP 1555
CVODE Benchmark Run Time 63.33 HH
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