Primary visual area layer 4 spiny 476054887 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 4
Keywords: Mus musculus, Scnn1a-Tg2-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001460
Cell_478047737.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001460
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Accommodating Wide AP Multi-Spikers (awMS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -85.47 mV
Rheobase Current Interval (0.06729, 0.07050] nA
Threshold Current Interval (0.76172, 0.82031] nA
Bias Current (to -80.00 mV) 0.0297 nA
Testing Temperature 34.0 °C
Stability Interval [-6.875, 15.0] nA
AP 1-2 Amplitude Drop -0.5979 mV
AP 1 Steady State Amplitude Change 7.1344 mV
AP 1 Amplitude 85.1329 mV
AP 1 Width at Half Height 0.5200 ms
AP 1 Width (Peak To Trough) 8.3600 ms
AP 1 Rate of Change Peak to Trough -11.2762 mV/ms
AP 1 AHP Depth 9.1359 mV
AP2 Amplitude 85.7308 mV
AP2 Width at Half Height 0.5300 ms
AP 2 Width (Peak to Trough) 16.4600 ms
AP 2 Rate of Change Peak to Trough -5.9978 mV/ms
AP 2 AHP Depth 12.9932 mV
AP 1-2 Amplitude Change Percent 0.7023 %
AP 1-2 Half Width Change Percent 1.9231 %
AP 1-2 Rate of Change Peak to Trough Percent Change -46.8098 %
AP 1-2 AHP Depth Percent Change 42.2217 %
Input Resistance 183.7693 MΩ
AP 1 Delay Mean 49.7100 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 69.6000 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 35.3200 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -25.0000 %
Steady State Accommodation Mean -25.0000 %
Accommodation Rate to Steady State -0.0426 %/ms
Accommodation at Steady State Mean -61.2941 %
Accommodation Rate Mean at Steady State 134.9389 ms
ISI CV 6.5050
ISI Median 67.0100 ms
ISI Burst Mean Change 155.1533 %
Spike Rate (Strong Stimulation) 57.5000 Hz
AP 1 Delay Mean (Strong Stimulation) 16.0500 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 21.4400 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 4.6650 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2073.2700 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 4732.33 µm2
Number of Stems 11.0
Number of Bifurcations 34.0
Number of Branches 79.0
Overall Width 191.296 µm
Overall Height 532.321 µm
Overall Depth 96.76 µm
Average Diameter 0.382737 µm
Total Length 3466.35 µm
Total Surface 4513.6 µm2
Total Volume 1636.28 µm3
Max Euclidean Distance 476.691 µm
Max Path Distance 517.344 µm
Max Branch Order 9.0
Average Contraction 0.913739
Total Fragmentation 2749.0
Partition Asymmetry 0.482353
Average Rall's Ratio 2.56808
Average Bifurcation Angle Local 75.0104 °
Average Bifurcation Angle Remote 58.3682 °
Fractal Dimension 1.02427
Complexity Summary
State Equations 208
Optimal Time-Step 0.02444 ms
Relative Complexity 14.15 HH
Model Size
Sections 78
Compartments 180
State Equations 208
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02444 ms
Optimal Time-Step Error 1.66 %
Optimal Time-Step Benchmark Run Time 14.15 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 3.02 %
Max. Stable Time-Step Benchmark Run Time 10.80 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 4392 Hz
CVODE Steps Per AP 783
CVODE Benchmark Run Time 27.77 HH
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