Primary visual area layer 6a spiny 471789504 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 6a
Keywords: Mus musculus, Ntsr1-Cre_GN220
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001457
Cell_472430904.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001480
Nap.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001490
NaTs.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001523
Im.channel.nml
( view NeuroML )
NMLCH001528
K_P.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001457
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Regular Spikers (RS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -85.44 mV
Rheobase Current Interval (0.14832, 0.15106] nA
Threshold Current Interval (0.64453, 0.70312] nA
Bias Current (to -80.00 mV) 0.0321 nA
Testing Temperature 34.0 °C
Stability Interval [-2.5, 15.0] nA
AP 1-2 Amplitude Drop 3.4240 mV
AP 1 Steady State Amplitude Change 5.9018 mV
AP 1 Amplitude 69.0917 mV
AP 1 Width at Half Height 0.9400 ms
AP 1 Width (Peak To Trough) 6.4300 ms
AP 1 Rate of Change Peak to Trough -12.3785 mV/ms
AP 1 AHP Depth 10.5017 mV
AP2 Amplitude 65.6677 mV
AP2 Width at Half Height 0.9500 ms
AP 2 Width (Peak to Trough) 7.5100 ms
AP 2 Rate of Change Peak to Trough -10.7108 mV/ms
AP 2 AHP Depth 14.7707 mV
AP 1-2 Amplitude Change Percent -4.9557 %
AP 1-2 Half Width Change Percent 1.0638 %
AP 1-2 Rate of Change Peak to Trough Percent Change -13.4719 %
AP 1-2 AHP Depth Percent Change 40.6502 %
Input Resistance 170.5254 MΩ
AP 1 Delay Mean 25.2700 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 46.7100 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 32.4250 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -14.2857 %
Steady State Accommodation Mean -14.2857 %
Accommodation Rate to Steady State -0.0929 %/ms
Accommodation at Steady State Mean -70.0183 %
Accommodation Rate Mean at Steady State 47.7736 ms
ISI CV 6.3512
ISI Median 64.3400 ms
ISI Burst Mean Change 102.4720 %
Spike Rate (Strong Stimulation) 41.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 5.6100 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 14.9700 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 11.3100 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2059.5300 ms
Frequency Filter Type High-Pass
Frequency Filter Pass Above 47.6331 Hz
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 5496.81 µm2
Number of Stems 6.0
Number of Bifurcations 32.0
Number of Branches 70.0
Overall Width 155.625 µm
Overall Height 858.394 µm
Overall Depth 78.89 µm
Average Diameter 0.811358 µm
Total Length 3774.24 µm
Total Surface 10019.8 µm2
Total Volume 3724.05 µm3
Max Euclidean Distance 850.348 µm
Max Path Distance 940.518 µm
Max Branch Order 17.0
Average Contraction 0.877515
Total Fragmentation 3071.0
Partition Asymmetry 0.557382
Average Rall's Ratio 2.23538
Average Bifurcation Angle Local 68.2394 °
Average Bifurcation Angle Remote 86.2462 °
Fractal Dimension 1.03487
Complexity Summary
State Equations 212
Optimal Time-Step 0.00751 ms
Relative Complexity 30.41 HH
Model Size
Sections 70
Compartments 196
State Equations 212
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.00751 ms
Optimal Time-Step Error 0.17 %
Optimal Time-Step Benchmark Run Time 30.41 HH
 
Maximum Stable Time-Step 0.0625 ms
Maximum Stable Time-Step Error 1.59 %
Max. Stable Time-Step Benchmark Run Time 57.05 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 10936 Hz
CVODE Steps Per AP 693
CVODE Benchmark Run Time 26.83 HH
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