Primary visual area layer 5 aspiny 475517090 Cell

Model Type:
Cell
Neurolex IDs: Primary visual area layer 5
Keywords: Mus musculus, Sst-IRES-Cre
Publication: Gouwens, et. al. (2018) Systematic generation of biophysically detailed models for diverse cortical neuron types.
Authors:
Nathan W Gouwens   Jim Berg   David Feng   Staci A Sorensen   Hongkui Zeng   Michael J Hawrylycz   Christof Koch   Anton Arkhipov  
Translators: Nicholas Cain   Padraig Gleeson   Shreejoy Tripathy  
Sources:
Files:
Model ID NeuroML File
NMLCL001456
Cell_478043748.cell.nml
( view NeuroML )
NMLCH001436
Ca_HVA.channel.nml
( view NeuroML )
NMLCH001446
Ih.channel.nml
( view NeuroML )
NMLCH001465
Kv3_1.channel.nml
( view NeuroML )
NMLCH001471
pas.channel.nml
( view NeuroML )
NMLCH001473
Kv2like.channel.nml
( view NeuroML )
NMLCH001486
NaV.channel.nml
( view NeuroML )
NMLCH001487
SK.channel.nml
( view NeuroML )
NMLCH001511
Ca_LVA.channel.nml
( view NeuroML )
NMLCH001520
Im_v2.channel.nml
( view NeuroML )
NMLCH001529
K_T.channel.nml
( view NeuroML )
NMLCH001536
Kd.channel.nml
( view NeuroML )
NMLCN001518
CaDynamics.nml
( view NeuroML )
Notes: None
Model Id: NMLCL001456
Associated Channels:
Associated Synapses: None
Associated Networks: None
Current Clamp Response
Protocol:
Meta Protocol: -
Stimulus: -
Closest Electrophysiology Cluster
⇛Multi-Spikers (MS)
   ⇛Regular Multi-Spikers (rMS)
      ⇛Delayed Regular Spikers (dRS)
Differentiating Features
Models with Similar Electrophysiology Properties
All Electrophysiology Properties
Is Passive No
Is Intrinsically Spiking No
Resting Voltage -97.75 mV
Rheobase Current Interval (0.02975, 0.03204] nA
Threshold Current Interval (0.52734, 0.58594] nA
Bias Current (to -80.00 mV) 0.0192 nA
Testing Temperature 34.0 °C
Stability Interval [-2.8125, 15.0] nA
AP 1-2 Amplitude Drop 0.1856 mV
AP 1 Steady State Amplitude Change 1.2301 mV
AP 1 Amplitude 68.3480 mV
AP 1 Width at Half Height 0.4100 ms
AP 1 Width (Peak To Trough) 3.4600 ms
AP 1 Rate of Change Peak to Trough -25.9986 mV/ms
AP 1 AHP Depth 21.6071 mV
AP2 Amplitude 68.1624 mV
AP2 Width at Half Height 0.4100 ms
AP 2 Width (Peak to Trough) 3.6700 ms
AP 2 Rate of Change Peak to Trough -24.6134 mV/ms
AP 2 AHP Depth 22.1690 mV
AP 1-2 Amplitude Change Percent -0.2716 %
AP 1-2 Half Width Change Percent 0.0000 %
AP 1-2 Rate of Change Peak to Trough Percent Change -5.3278 %
AP 1-2 AHP Depth Percent Change 2.6002 %
Input Resistance 1025.9251 MΩ
AP 1 Delay Mean 82.7600 ms
AP 1 Delay SD 0.0000 ms
AP 2 Delay Mean 149.7300 ms
AP 2 Delay SD 0.0000 ms
Burst 1 ISI Mean 68.4150 ms
Burst 1 ISI SD 0.0000 ms
Initial Accommodation Mean -20.0000 %
Steady State Accommodation Mean 0.0000 %
Accommodation Rate to Steady State 0.0000 %/ms
Accommodation at Steady State Mean -30.5907 %
Accommodation Rate Mean at Steady State 456.0338 ms
ISI CV 10.3463
ISI Median 90.5700 ms
ISI Burst Mean Change 4.3154 %
Spike Rate (Strong Stimulation) 34.0000 Hz
AP 1 Delay Mean (Strong Stimulation) 29.5300 ms
AP 1 Delay SD (Strong Stimulation) 0.0000 ms
AP 2 Delay Mean (Strong Stimulation) 50.8200 ms
AP 2 Delay SD (Strong Stimulation) 0.0000 ms
Burst 1 ISI Mean (Strong Stimulation) 25.5450 ms
Burst 1 ISI SD (Strong Stimulation) 0.0000 ms
Ramp First Spike Time 2101.9600 ms
Frequency Filter Type Constant
3D Structure and Propagation of Activity
L-Measure Properties
Soma Surface 3415.8 µm2
Number of Stems 8.0
Number of Bifurcations 20.0
Number of Branches 48.0
Overall Width 217.015 µm
Overall Height 335.949 µm
Overall Depth 43.81 µm
Average Diameter 0.429516 µm
Total Length 2474.16 µm
Total Surface 3641.37 µm2
Total Volume 1267.44 µm3
Max Euclidean Distance 301.065 µm
Max Path Distance 342.871 µm
Max Branch Order 5.0
Average Contraction 0.91363
Total Fragmentation 2061.0
Partition Asymmetry 0.557143
Average Rall's Ratio 2.1075
Average Bifurcation Angle Local 80.5261 °
Average Bifurcation Angle Remote 61.043 °
Fractal Dimension 1.02325
Complexity Summary
State Equations 158
Optimal Time-Step 0.02256 ms
Relative Complexity 12.31 HH
Model Size
Sections 48
Compartments 130
State Equations 158
Fixed Time-Step Run Time vs. Voltage Potential Error
Run Time-vs-Error Optimal Time-Step 0.02256 ms
Optimal Time-Step Error 0.82 %
Optimal Time-Step Benchmark Run Time 12.31 HH
 
Maximum Stable Time-Step 0.5 ms
Maximum Stable Time-Step Error 3.55 %
Max. Stable Time-Step Benchmark Run Time 8.68 HH
Variable Time-Step Complexity
CVODE Steady State Step Frequency 4122 Hz
CVODE Steps Per AP 1490
CVODE Benchmark Run Time 34.73 HH
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